Evidence map›Paper›PMID 34815780›Full record

ArticleTheranostics2021

Practical considerations for quantitative clinical SPECT/CT imaging of alpha particle emitting radioisotopes.

Nadia Benabdallah, William Scheve, Nicholas Dunn, Delynn Silvestros, Paul Schelker, Diane Abou, Uday Jammalamadaka, Richard Laforest, Zekun Li, Jonathan Liu and 10 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

  1. Predicting tumour and organ dose in α-radiopharmaceutical therapy: aEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Optimisation of Q.Clear (BSREM) Reconstruction Parameters forBioengineering (Basel, Switzerland) · 2026
    Article
  3. Review
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  12. Image-based dosimetry for [European journal of nuclear medicine and molecular imaging · 2024
    Article
  13. Article
  14. Article
  15. EANM guidance document: dosimetry for first-in-human studies and early phase clinical trials.European journal of nuclear medicine and molecular imaging · 2024
    Article
  16. Article
  17. Article
  18. SPECT at the speed of PET: a feasibility study of CZT-based whole-body SPECT/CT in the postEuropean journal of nuclear medicine and molecular imaging · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 2 institutions in 1 country.

Nadia BenabdallahDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri.
William ScheveBarnes-Jewish Hospital, St. Louis, Missouri.
Nicholas DunnBarnes-Jewish Hospital, St. Louis, Missouri.
Delynn SilvestrosBarnes-Jewish Hospital, St. Louis, Missouri.
Paul SchelkerBarnes-Jewish Hospital, St. Louis, Missouri.
Diane AbouDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri.
Uday JammalamadakaDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri.
Richard LaforestDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri.
Zekun LiDepartment of Biomedical Engineering, Washington University, St. Louis, Missouri.
Jonathan LiuDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri.
David H BallardDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri.
Nichole M MaughanDepartment of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri.
Hiram GayDepartment of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri.
Brian C BaumannDepartment of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri.
Robert F HobbsRadiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Buck RogersDepartment of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri.
Amir IravaniDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri.
Abhinav K JhaDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri.
Farrokh DehdashtiDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri.
Daniel L J ThorekDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri.
Washington University in St. Louis · USBarnes-Jewish Hospital · US

Funding

Training OPportunities in Translational Imaging Education and Research (TOP-TIER)T32EB021955 · NIBIB · WASHINGTON UNIVERSITY · PI Hongyu An, Joseph Edward Ippolito · 2017 to 2026
$2.4M
The Radium-223 Combination Therapy Space; Improving Response and Clarifying ToxicitiesR01CA240711 · NCI · WASHINGTON UNIVERSITY · PI MICHALSKI, JEFF M., THOREK, DANIEL LYNDON JAFFE · 2020 to 2024
$2.2M
Opening the Therapeutic Window for PSMA-Targeted Molecular RadiotherapyR01CA229893 · NCI · WASHINGTON UNIVERSITY · PI THOREK, DANIEL LYNDON JAFFE · 2019 to 2024
$1.9M
Kallikrein-Targeted Alpha-Particle Therapy of Late-Stage Prostate CancerR01CA201035 · NCI · WASHINGTON UNIVERSITY · PI THOREK, DANIEL LYNDON JAFFE · 2017 to 2020
$1.4M
NCI NIH HHS R01 CA201035NCI NIH HHS R01 CA229893NCI NIH HHS R01 CA240711NIBIB NIH HHS T32 EB021955
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ActiniumAlpha ParticlesAnimalsBiological AvailabilityCalibrationHumansImage Processing, Computer-AssistedPhantoms, ImagingRadioisotopesRadiopharmaceuticalsRadiumSingle Photon Emission Computed Tomography Computed TomographyThoriumTomography, X-Ray ComputedActiniumActinium-225RadioisotopesRadiopharmaceuticalsRadiumRadium-223ThoriumThorium-227Actinium-225quantitative SPECT/CTradiopharmaceutical therapiesRadium-223Thorium-227

Identifiers

PMID34815780
PMCPMC8581409
OpenAlexW3159736416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.