Evidence map›Paper›PMID 34815769›Full record

ArticleExperimental and therapeutic medicine2022

Radiofrequency thermocoagulation for the treatment of trigeminal neuralgia.

Zhengming Wang, Zhijia Wang, Kai Li, Xu Su, Chao Du, Yu Tian

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Controversies in Trigeminal Neuralgia: A Review.Asian journal of neurosurgery · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Modern Approaches to the Treatment of Acute Facial Pain.Current pain and headache reports · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zhengming WangDepartment of Neurosurgery, The Third Hospital of Jilin University and China-Japan Union Hospital, Changchun, Jilin 130033, P.R. China.
Zhijia WangDepartment of Radiation, The Third Hospital of Jilin University and China-Japan Union Hospital, Changchun, Jilin 130033, P.R. China.
Kai LiDepartment of Anesthesia, The Third Hospital of Jilin University and China-Japan Union Hospital, Changchun, Jilin 130033, P.R. China.
Xu SuDepartment of Neurosurgery, The Third Hospital of Jilin University and China-Japan Union Hospital, Changchun, Jilin 130033, P.R. China.
Chao DuDepartment of Neurosurgery, The Third Hospital of Jilin University and China-Japan Union Hospital, Changchun, Jilin 130033, P.R. China.
Yu TianDepartment of Neurosurgery, The Third Hospital of Jilin University and China-Japan Union Hospital, Changchun, Jilin 130033, P.R. China.
Jilin University · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although microvascular decompression (MVD) should be considered as the first-line treatment for classic trigeminal neuralgia (TN) owing to neurovascular compression of the trigeminal nerve, an increasing number of surgeons prefer radiofrequency thermocoagulation (RFT). RFT is a Gasserian ganglion-level ablative intervention that may achieve immediate pain relief for TN. It is used for emergency management when MVD is not suitable for the patient. As the gold surgical standard of classic trigeminal neuralgia, MVD has the advantage of longer efficacy. However, there are currently no high-quality controlled trials to evaluate the efficacy of MVD and RFT. For the present systematic review, the PubMed, Embase and Cochrane databases (all entries up until July 31, 2020) were searched to identify studies related to RFT in order to provide valuable information for clinical decision-making. The efficacy of the RFT method was evaluated in terms of the initial pain relief percentage, recurrence rate and follow-up time. Furthermore, the incidence rate of various postoperative complications was retrieved. RFT was used for a wider range of applications than MVD, including use for primary (owing to neurovascular compression of the trigeminal nerve), idiopathic and secondary (due to primary neurological diseases) TN, and provided a high rate of initial pain relief and long-term pain control. Although this method has several side effects, the incidence of complications could be reduced by precise cannulation. Furthermore, the complications that occurred were not permanent. Thus, RFT is a safe and effective minimally invasive method of pain relief for patients with TN.

Indexed as

ablative interventionscomplicationsGasserian ganglionradiofrequency thermocoagulationrecurrence ratetrigeminal neuralgia

Identifiers

PMID34815769
PMCPMC8593925
OpenAlexW3210514901

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.