Evidence map›Paper›PMID 34815701›Full record

ArticleInternational journal of general medicine2021

Association of CSMD1 with Tumor Mutation Burden and Other Clinical Outcomes in Gastric Cancer.

Xuning Wang, Shixiang Wang, Yalin Han, Maolin Xu, Peng Li, Mu Ke, Zhipeng Teng, Pu Huang, Ziyan Diao, Yongfeng Yan and 6 more

Abstract read
In one paragraph

Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Identification of a Novel Risk Model: A Five-Gene Prognostic Signature for Pancreatic Cancer.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Xuning Wang *The Air Force Hospital of Northern Theater PLA, Shenyang, People's Republic of China.ORCID 0000-0001-5510-8172
Shixiang Wang *School of Life Science and Technology, ShanghaiTech University, Shanghai, People's Republic of China.
Yalin HanThe Air Force Hospital of Northern Theater PLA, Shenyang, People's Republic of China.
Maolin XuThe Air Force Hospital of Northern Theater PLA, Shenyang, People's Republic of China.
Peng LiThe Air Force Hospital of Northern Theater PLA, Shenyang, People's Republic of China.
Mu KeThe Air Force Hospital of Northern Theater PLA, Shenyang, People's Republic of China.ORCID 0000-0002-1430-9477
Zhipeng TengThe Air Force Hospital of Northern Theater PLA, Shenyang, People's Republic of China.
Pu HuangThe Air Force Hospital of Northern Theater PLA, Shenyang, People's Republic of China.
Ziyan DiaoDepartment of General Surgery, The First Center of Chinese PLA General Hospital, Beijing, People's Republic of China.
Yongfeng YanThe Air Force Hospital of Northern Theater PLA, Shenyang, People's Republic of China.
Qingyu MengThe Air Force Hospital of Northern Theater PLA, Shenyang, People's Republic of China.
Yanshen KuangThe Air Force Hospital of Northern Theater PLA, Shenyang, People's Republic of China.
Wei ZhengThe Air Force Hospital of Northern Theater PLA, Shenyang, People's Republic of China.
Hongyi LiuThe Air Force Hospital of Northern Theater PLA, Shenyang, People's Republic of China.
Xuesong LiuSchool of Life Science and Technology, ShanghaiTech University, Shanghai, People's Republic of China.
Baoqing JiaThe Air Force Hospital of Northern Theater PLA, Shenyang, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmunotherapy is considered as a powerful and promising clinical approach for the treatment of gastric cancer (GC). However, it is still challenging to precisely screen patients who potentially benefit from immune checkpoint therapy (ICT). Identification of potential biomarkers for selecting patients sensitive to immunotherapy was urgently needed.

methodsPublic sequence data and corresponding clinical data were used to explore the potential biomarkers for immunotherapy.

resultsWe found that

conclusionCSMD1 mutation may act as a novel biomarker for assessing the survival and immune therapy response in patients with gastric cancer.

Indexed as

CSMD1gastric cancerPDL1tumor mutation burden

Identifiers

PMID34815701
PMCPMC8605807

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.