Evidence map›Paper›PMID 34815497›Full record

ArticleScientific reports2021

Epitachophoresis is a novel versatile total nucleic acid extraction method.

Vladimira Datinska, Pantea Gheibi, Keynttisha Jefferson, Jaeyoung Yang, Sri Paladugu, Carolina Dallett, Ivona Voracova, Frantisek Foret, Yann Astier

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vladimira Datinska *Roche Sequencing Solution, Pleasanton, CA, 94588, USA.
Pantea Gheibi *Roche Sequencing Solution, Pleasanton, CA, 94588, USA.
Keynttisha Jefferson *Roche Sequencing Solution, Pleasanton, CA, 94588, USA.
Jaeyoung YangRoche Sequencing Solution, Pleasanton, CA, 94588, USA.
Sri PaladuguRoche Sequencing Solution, Pleasanton, CA, 94588, USA.
Carolina DallettRoche Sequencing Solution, Pleasanton, CA, 94588, USA.
Ivona VoracovaInstitute of Analytical Chemistry, Czech Academy of Sciences, 602 00, Brno, Czech Republic.
Frantisek ForetInstitute of Analytical Chemistry, Czech Academy of Sciences, 602 00, Brno, Czech Republic.
Yann AstierRoche Sequencing Solution, Pleasanton, CA, 94588, USA. astier.yann@gmail.com.

Funding

Institutional support of Institute of Analytical Chemistry RVO 68081715
6 · The paper itself

Abstract

Epitachophoresis is a novel next generation extraction system capable of isolating DNA and RNA simultaneously from clinically relevant samples. Here we build on the versatility of Epitachophoresis by extracting diverse nucleic acids ranging in lengths (20 nt-290 Kbp). The quality of extracted miRNA, mRNA and gDNA was assessed by downstream Next-Generation Sequencing.

Indexed as

Colorectal NeoplasmsDNA, NeoplasmHigh-Throughput Nucleotide SequencingHumansLung NeoplasmsRNA, NeoplasmTissue FixationTumor Cells, CulturedDNA, NeoplasmRNA, Neoplasm

Identifiers

PMID34815497
PMCPMC8611068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.