ArticleScientific reports2021
Ultrasound estimated subcutaneous and visceral adipose tissue thicknesses and risk of pre-eclampsia.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Maternal adiposity measures and hypertensive disorders of pregnancy: a meta-analysis.BMC pregnancy and childbirth · 2024Pooled it
- HDL-C and visceral adipose tissue as combined predictors of visceral fat changes following laparoscopic sleeve gastrectomy.BMC surgery · 2025Trial
- Prenatal adipose tissue estimation using early second trimester anthropometry.European journal of clinical nutrition · 2026Article
- Abdominal fat thickness predicts the risk of pregnancy-associated hypertension: A prospective cohort study.Asia Pacific journal of clinical nutrition · 2026Article
- Update on Obesity and Its Relationship to Atherosclerotic Cardiovascular Disease and Associated Risk Factors.Journal of clinical medicine · 2026Review
- First-trimester adipocytokine levels as predictive biomarkers for preeclampsia: a prospective case-control study.European journal of medical research · 2026Article
- Consistency of Ultrasound Measurements of Fat Thickness in Different Postures.Current medical imaging · 2025Article
- Influence of Adipose Tissue on Early Metabolic Programming: Conditioning Factors and Early Screening.Diagnostics (Basel, Switzerland) · 2023Review
- Age at Menarche Mediating Visceral Adipose Tissue's Influence on Pre-eclampsia: A Mendelian Randomization Study.The Journal of clinical endocrinology and metabolism · 2023Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early identification of high-risk pregnancies enables identification of those who would benefit from aspirin prophylaxis and increased surveillance for pre-eclampsia. A high body mass index (BMI) is a well-known predictor for pre-eclampsia. However, if abdominal adipose tissue distribution is associated with pre-eclampsia is limited investigated. Subcutaneous adipose tissue (SAT) thickness and visceral adipose tissue (VAT) thickness were measured by ultrasound on 3777 women at around 18 gestational weeks. SAT thickness was measured from the skin to linea alba and VAT from linea alba to the anterior aortic wall. The risk of developing pre-eclampsia (de novo hypertension at ≥ 20 gestational weeks in combination with proteinuria) was evaluated by logistic regression and expressed as odds ratio (OR) with 95% confidence intervals (CI). The risk of pre-eclampsia increased by 79% for every cm in SAT thickness (OR 1.79; 95% CI 1.48-2.17) and by 23% for every cm VAT thickness (OR 1.23; 95% CI 1.11-1.35). After adjustment for maternal age, parity, BMI, smoking and country of birth, the association between SAT thickness and pre-eclampsia remained (AOR 1.35; 95% CI 1.02-1.79). Greater SAT thickness measured with second trimester ultrasound is associated with increased risk of developing pre-eclampsia. The measurement may improve prediction models for pre-eclampsia.
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