Evidence map›Paper›PMID 34815358›Full record

ArticleRNA (New York, N.Y.)2022

Discovery and initial characterization of YloC, a novel endoribonuclease in

Shakti Ingle, Shivani Chhabra, Jiandong Chen, Michael B Lazarus, Xing Luo, David H Bechhofer

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Structural and biophysical insights into the unique RNase YicC.bioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Shakti IngleDepartment of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.ORCID 0000-0003-1541-5324
Shivani ChhabraDepartment of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.ORCID 0000-0002-5023-3393
Jiandong ChenDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.ORCID 0000-0002-5144-7537
Michael B LazarusDepartment of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Xing LuoLaboratory of Molecular Biology, National Cancer Institute, Bethesda, Maryland 20892, USA.
David H BechhoferDepartment of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.ORCID 0000-0002-8502-2430
Icahn School of Medicine at Mount Sinai · USNational Cancer Institute · USUniversity of Pennsylvania · US

Funding

Chemical and structural tools to study energy homeostasis pathways in cancer and diabetesR35GM124838 · NIGMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Michael Block Lazarus · 2017 to 2026
$5.2M
Mechanism of 3' exonucleolytic mRNA turnover in Bacillus subtilisR01GM125655 · NIGMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BECHHOFER, DAVID H · 2018 to 2021
$1.4M
NIGMS NIH HHS R01 GM125655NIGMS NIH HHS R35 GM124838
6 · The paper itself

Abstract

The

Indexed as

Bacillus subtilisBacterial ProteinsEndoribonucleasesEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialMicroorganisms, Genetically-ModifiedMutationRibonucleasesRNA, BacterialRNA StabilitySubstrate SpecificityViral Nonstructural ProteinsBacterial ProteinsEndoribonucleasesEscherichia coli Proteinsnidoviral uridylate-specific endoribonucleaseRibonucleasesRNA, BacterialViral Nonstructural ProteinsBacillusbacteriaendoribonucleaseoligomersmall RNA processing

Identifiers

PMID34815358
PMCPMC8906540
OpenAlexW3216902469

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.