Evidence map›Paper›PMID 34815278›Full record

ArticleBMJ open2021

Science, healthcare system, and government effectiveness perception and COVID-19 vaccination acceptance and hesitancy in a global sample: an analytical cross-sectional analysis.

Timothy D Dye, Monica Barbosu, Shazia Siddiqi, José G Pérez Ramos, Hannah Murphy, Lisette Alcántara, Eva Pressman

Abstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Between intention and action: the paradoxes of female vaccination.Archives of public health = Archives belges de sante publique · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Timothy D DyeObstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York, USA tim_dye@urmc.rochester.edu.ORCID 0000-0002-9801-4712
Monica BarbosuObstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York, USA.
Shazia SiddiqiObstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York, USA.
José G Pérez RamosObstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York, USA.ORCID 0000-0002-6654-6984
Hannah MurphyObstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York, USA.
Lisette AlcántaraObstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York, USA.
Eva PressmanObstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York, USA.

Funding

The University of Rochester's Clinical and Translational Science InstituteUL1TR002001 · NCATS · UNIVERSITY OF ROCHESTER · PI WILSON, KAREN M., ZAND, MARTIN S · 2016 to 2024
$34.6M
Rochester Partnership to Advance Research and Academic Careers in Deaf ScholarsK12GM106997 · NIGMS · UNIVERSITY OF ROCHESTER · PI BUCKLEY, GERARD J., DEWHURST, STEPHEN · 2015 to 2024
$6.9M
NRSA Training CoreTL1TR002000 · NCATS · UNIVERSITY OF ROCHESTER · PI THAKAR, JUILEE, VAN WIJNGAARDEN, EDWIN · 2016 to 2024
$4.1M
NCATS NIH HHS TL1 TR002000NCATS NIH HHS UL1 TR002001NIGMS NIH HHS K12 GM106997
6 · The paper itself

Abstract

backgroundDeterminants of COVID-19 vaccine acceptance are complex; how perceptions of the effectiveness of science, healthcare and government impact personal COVID-19 vaccine acceptance is unclear, despite all three domains providing critical roles in development, funding and provision, and distribution of COVID-19 vaccine.

objectiveTo estimate impact of perception of science, healthcare systems, and government along with sociodemographic, psychosocial, and cultural characteristics on vaccine acceptance.

designWe conducted a global nested analytical cross-sectional study of how the perceptions of healthcare, government and science systems have impacted COVID-19 on vaccine acceptance.

settingGlobal Facebook, Instagram and Amazon Mechanical Turk (mTurk) users from 173 countries.

participants7411 people aged 18 years or over, and able to read English, Spanish, Italian, or French. MEASUREMENTS: We used Χ

resultsAfter controlling for confounding, attitude toward science was a strong predictor of vaccine acceptance, more so than other attitudes, demographic, psychosocial or COVID-19-related variables (aOR: 2.1; 95% CI: 1.8 to 2.5). The rationale for science effectiveness was dominated by vaccine narratives, which were uncommon in other domains. LIMITATIONS: This study did not include participants from countries where Facebook and Amazon mTurk are not available, and vaccine acceptance reflected intention rather than actual behaviour.

conclusionsAs our findings show, vaccine-related issues dominate public perception of science's impact around COVID-19, and this perception of science relates strongly to the decision to obtain vaccination once available.

Indexed as

COVID-19COVID-19 VaccinesCross-Sectional StudiesDelivery of Health CareGovernmentHumansPerceptionSARS-CoV-2VaccinationCOVID-19 VaccinesCOVID-19international health servicespublic health

Identifiers

PMID34815278
PMCPMC8611238

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.