ArticleBMJ case reports2021
Mitral valve-in-valve implantation during pregnancy.
Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Novel Use of Valve-in-Valve Transcatheter Mitral Valve Replacement for Severe Bioprosthetic Mitral Valve Stenosis During Pregnancy: A Case Report.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Article
- Pregnancy Complicated by Severe Bioprosthetic Mitral Valve Stenosis Treated by Valve-in-Valve Transcatheter Mitral Valve Replacement.JACC. Case reports · 2025Article
- Mitral Transcatheter Edge-to-Edge Repair in a Pregnant Woman: Procedure and Pregnancy Outcomes.JACC. Case reports · 2025Article
- Transcatheter mitral valve-in-valve for pregnancy with anti-phospholipid syndrome: a case report.Journal of cardiothoracic surgery · 2024Article
- Reproductive Health in Congenital Heart Disease: Preconception, Pregnancy, and Postpartum.Journal of cardiovascular development and disease · 2023Review
- Catheter-Based Interventions for the Management of Valvular Heart Disease During Pregnancy.JACC. Advances · 2022Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 32-year-old, 11-week pregnant African woman with known rheumatic heart disease presented to the emergency department with worsening shortness of breath on exertion. She had undergone a double bioprosthetic valve replacement and left atrial appendage resection 8 years prior for severe mitral stenosis, moderate mitral regurgitation and moderate aortic regurgitation. A transo-oesophageal echocardiography at this presentation confirmed a morphologically calcified and stenosed mitral bioprosthesis, with moderate stenosis of her aortic bioprosthesis. Her multidisciplinary team, including cardiologists, cardiothoracic surgeons and obstetricians, came to a consensus decision to proceed with a transseptal transcatheter valve implantation within the mitral valve prosthesis (valve-in-valve implantation). Transthoracic echocardiography performed 2 months post procedure showed satisfactory mitral valve gradients and at 30 weeks' gestation, she successfully delivered her fifth child. 2 years later, the valve in valve complex is still functioning well.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.