ArticleApplied nursing research : ANR2021
Factors associated with symptom distress in women with breast cancer prior to initiation of chemotherapy.
Article in Applied nursing research : ANR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Financial strain measures and associations with adult health: A systematic literature review.Social science & medicine (1982) · 2025Pooled it
- A Decision Tree Analysis on Symptom Experience of Asian American Breast Cancer Survivors.Western journal of nursing research · 2023Trial
- Assessing Racial Differences in Psychological Distress and Problem Items among Breast Cancer Survivors at Adjuvant Endocrine Therapy Initiation.Clinical breast cancer · 2026Observational
- Impact of age and treatment-related adverse events on financial toxicity among patients with breast cancer: a systematic review.Journal of cancer survivorship : research and practice · 2025Article
- The Effect of Race and Area Deprivation on Symptom Profiles Over the Course of Early-Stage Breast Cancer.Journal of pain and symptom management · 2025Article
- Social Needs in Cancer Survivors: A Scoping Review and Future Directions.Current oncology reports · 2025Article
- Brain-Derived Neurotrophic Factor rs6265 polymorphism is associated with severe cancer-related fatigue and neuropathic pain in female cancer survivors.Journal of cancer survivorship : research and practice · 2024Article
- Associations of brain-derived neurotrophic factor rs6265 polymorphism and cognitive function in breast cancer survivors from a cross-sectional study.Cancer medicine · 2024Article
- The Effect of Race and Area Deprivation on Symptom Profiles over the Course of Early-Stage Breast Cancer.Research square · 2023Article
- Identification of age differences in cancer-related symptoms in women undergoing chemotherapy for breast cancer in China.BMC women's health · 2023Article
- Article
- Translational Genomic Research: The Association between Genetic Profiles and Cognitive Functioning or Cardiac Function Among Breast Cancer Survivors Completing Chemotherapy.Biological research for nursing · 2022Article
- Interpersonal Processes of Care Disparities, Symptom Distress, and Chemotherapy Dosing in Women With Early-Stage Breast Cancer.Nursing researchArticle
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundSymptom distress in women with breast cancer is associated with early discontinuation of chemotherapy and may influence treatment outcomes. Describing racial differences in prechemotherapy symptom distress and examining contextual variables of the symptom experience may inform our understanding of the complex problem of racial disparities in breast cancer.
aimTo determine if perceived social support, healthcare system distrust, and economic hardship predict symptom distress in women with breast cancer prior to their first chemotherapy treatment.
designDescriptive, correlational, cross-sectional.
methodsBaseline data (N = 119) was used from a multisite, longitudinal study comparing the symptom experience and ability to receive chemotherapy of Black and White women with breast cancer (R01MD012245; Rosenzweig, PI). Measures included the Symptom Distress Scale, Interpersonal Support Evaluation List, Health Care System Distrust Scale, and Psychological Sense of Economic Hardship scale. The analysis consisted of multiple regression and a t-test.
resultsOn average, participants reported five symptoms prior to chemotherapy. Black women reported higher symptoms distress than White women; t(68.34) = 2.15, p = 0.035. The model explained 26% of variance in symptom distress; F(5, 112) = 9.01, p < 0.001. While controlling for age and race, greater perceived economic hardship contributed to higher symptom distress (β = 0.36, p = 0.001, 95% CI: 0.34 to 1.34). Race, health care system distrust and social support did not significantly predict symptom distress.
conclusionAssessment of perceived financial hardship prior to beginning chemotherapy is critical to identify those patients at risk for greater symptom distress.
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