ArticleProceedings. Biological sciences2021
Insect-host control of obligate, intracellular symbiont density.
Article in Proceedings. Biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed.
- Crosstalk in the cold: host-microbe interactions in insect diapause.Annals of the Entomological Society of America · 2026Review
- Exploiting peptide chirality and transport to dissect the complex mechanism of action of host peptides on bacteria.PLoS genetics · 2025Article
- Evolutionary dynamics of obligate endosymbiosis in the psyllid genus Cacopsylla.Communications biology · 2025Article
- Symbionts with eroded genomes adjust gene expression according to host life-stage and environment.EMBO reports · 2025Article
- Exploiting Peptide Chirality and Transport to Dissect the Complex Mechanism of Action of Host Peptides on Bacteria.bioRxiv : the preprint server for biology · 2025Article
- Evolutionary Convergence of Nutritional Symbionts in Ticks.Environmental microbiology reports · 2025Article
- How do host age and nutrition affect density regulation of obligate versus facultative bacterial symbionts? Insights from the tsetse fly.ISME communications · 2025Article
- Effect of Microsporidia MB infection on the development and fitness of Anopheles arabiensis under different diet regimes.Parasites & vectors · 2024Article
- Describing endosymbiont-host interactions within the parasitism-mutualism continuum.Ecology and evolution · 2024Article
- PacBio Hi-Fi genome assembly of Sipha maydis, a model for the study of multipartite mutualism in insects.Scientific data · 2024Article
- Barley Yellow Dwarf Virus Influences Its Vector's Endosymbionts but Not Its Thermotolerance.Microorganisms · 2023Article
- A theoretical model for host-controlled regulation of symbiont density.Journal of evolutionary biology · 2023Article
- Know When You Are Too Many: Density-Dependent Release of Pheromones During Host Colonisation by the European Spruce Bark Beetle, Ips typographus (L.).Journal of chemical ecology · 2023Article
- Seasonal wild dance of dual endosymbionts in the pear psyllid Cacopsylla pyricola (Hemiptera: Psylloidea).Scientific reports · 2023Article
- Host plant-mediated effects onFrontiers in plant science · 2023Article
- Microbiome Analysis of the Bamboo AphidInsects · 2022Article
- Bacterial supergroup-specific "cost" ofEcology and evolution · 2022Article
- The Di-Symbiotic Systems in the AphidsMicroorganisms · 2022Article
- Compartmentalized into Bacteriocytes but Highly Invasive: the Puzzling Case of the Co-Obligate Symbiont Serratia symbiotica in the AphidMicrobiology spectrum · 2022Article
- For the road: calibrated maternal investment in light of extracellular symbiont transmission.Proceedings. Biological sciences · 2022Article
Corrections and comments
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Authors and funding
5 authors.
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Abstract
Many insects rely on intracellular bacterial symbionts to supplement their specialized diets with micronutrients. Using data from diverse and well-studied insect systems, we propose three lines of evidence suggesting that hosts have tight control over the density of their obligate, intracellular bacterial partners. First, empirical studies have demonstrated that the within-host symbiont density varies depending on the nutritional and developmental requirements of the host. Second, symbiont genomes are highly reduced and have limited capacity for self-replication or transcriptional regulation. Third, several mechanisms exist for hosts to tolerate, regulate and remove symbionts including physical compartmentalization and autophagy. We then consider whether such regulation is adaptive, by discussing the relationship between symbiont density and host fitness. We discuss current limitations of empirical studies for exploring fitness effects in host-symbiont relationships, and emphasize the potential for using mathematical models to formalize evolutionary hypotheses and to generate testable predictions for future work.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.