Evidence map›Paper›PMID 34813967›Full record

ArticleJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus2022

Chronic recurrent multifocal osteomyelitis causing optic neuropathy.

Joel Mudri, Jane Lock, Omkar Phadke, Kelly Rouster-Stevens, H Joon Kim, Jason H Peragallo

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Joel MudriDepartment of Ophthalmology, Royal Perth Hospital, Perth WA Australia. Electronic address: joel.mudri@health.wa.gov.au.
Jane LockDepartment of Ophthalmology, Royal Perth Hospital, Perth WA Australia; Department of Ophthalmology, Sir Charles Gairdner Hospital, Perth WA Australia; Department of Ophthalmology, Perth's Children's Hospital, Perth WA Australia.
Omkar PhadkeDepartment of Pediatrics Rheumatology, Emory University School of Medicine & Children's Healthcare of Atlanta, Atlanta, Georgia.
Kelly Rouster-StevensDepartment of Pediatrics Rheumatology, Emory University School of Medicine & Children's Healthcare of Atlanta, Atlanta, Georgia.
H Joon KimDepartment of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia.
Jason H PeragalloDepartment of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.
Emory University · USRoyal Perth Hospital · AU

Funding

P30-Core Grant for Vision Research Core CP30EY006360 · NEI · EMORY UNIVERSITY · PI NICKERSON, JOHN M · 1986 to 2025
$15.3M
VIsion Science Training in AtlantaT32EY007092 · NEI · EMORY UNIVERSITY · PI Machelle T. Pardue · 1985 to 2026
$4.6M
NEI NIH HHS P30 EY006360NEI NIH HHS T32 EY007092
6 · The paper itself

Abstract

We present the case of an 8-year-old girl with chronic recurrent multifocal osteomyelitis (CRMO) involving the orbit and facial bone and causing left optic neuropathy. She presented with intermittent left periorbital swelling and a history of CRMO diagnosed 5 years earlier. Her disease responded well to adalimumab; however, delayed presentation resulted in permanent unilateral optic nerve atrophy and reduced vision. Orbital inflammatory disease is a rare manifestation of CRMO, and early recognition of the disease and treatment may prevent irreversible vision loss.

Indexed as

Optic Nerve DiseasesOsteomyelitisChildChronic DiseaseFemaleHumansOptic NerveRare Diseases

Identifiers

PMID34813967
PMCPMC8976710
OpenAlexW3217178477

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.