Evidence map›Paper›PMID 34813753›Full record

ArticleCurrent biology : CB2021

Decision making: An analogue implementation of a drift-diffusion computation in the Drosophila mushroom body.

Nathan Buerkle, James M Jeanne

Abstract readComment
PubMed Publisher
In one paragraph

Article in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Spatiotemporal dynamics of locomotor decisions inbioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nathan BuerkleDepartment of Neuroscience, Yale University, 333 Cedar Street, New Haven, CT 06510, USA. Electronic address: nathan.buerkle@yale.edu.
James M JeanneDepartment of Neuroscience, Yale University, 333 Cedar Street, New Haven, CT 06510, USA. Electronic address: james.jeanne@yale.edu.
Yale University · US

Funding

Synaptic mechanisms of temporal pattern separationR01NS116584 · NINDS · YALE UNIVERSITY · PI JEANNE, JAMES MCCLURE · 2023 to 2024
$698k
NINDS NIH HHS R01 NS116584
6 · The paper itself

Abstract

A new study combines electrophysiology, optogenetics, and behavior to investigate a decision-making circuit in the fly brain, revealing all the major features predicted by drift-diffusion models. Strikingly, much of this computation takes place subthreshold, independent of action potentials.

Indexed as

Drosophila ProteinsMushroom BodiesAction PotentialsAnimalsDecision MakingDrosophilaDrosophila Proteins

Identifiers

PMID34813753
OpenAlexW3216391976

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.