Evidence map›Paper›PMID 34813591›Full record

ArticlePLoS medicine2021

Prevalence and determinants of healthcare avoidance during the COVID-19 pandemic: A population-based cross-sectional study.

Marije J Splinter, Premysl Velek, M Kamran Ikram, Brenda C T Kieboom, Robin P Peeters, Patrick J E Bindels, M Arfan Ikram, Frank J Wolters, Maarten J G Leening, Evelien I T de Schepper and 1 more

Open access · goldAbstract read
In one paragraph

Article in PLoS medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 1 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 1 synthesis or guideline pooled it, 148 citations in OpenAlex.

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  13. Self-Harm Presentations to a Pediatric Trauma Centre During the First Year of the COVID-19 Pandemic.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2025
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28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Marije J SplinterDepartment of Epidemiology, Erasmus MC-University Medical Center Rotterdam, Rotterdam, the Netherlands.ORCID 0000-0001-9067-7362
Premysl VelekDepartment of Epidemiology, Erasmus MC-University Medical Center Rotterdam, Rotterdam, the Netherlands.ORCID 0000-0001-8548-6211
M Kamran IkramDepartment of Epidemiology, Erasmus MC-University Medical Center Rotterdam, Rotterdam, the Netherlands.ORCID 0000-0003-0173-9571
Brenda C T KieboomDepartment of Epidemiology, Erasmus MC-University Medical Center Rotterdam, Rotterdam, the Netherlands.ORCID 0000-0001-9075-222X
Robin P PeetersDepartment of Internal Medicine, Erasmus MC-University Medical Center Rotterdam, Rotterdam, the Netherlands.
Patrick J E BindelsDepartment of General Practice, Erasmus MC-University Medical Center Rotterdam, Rotterdam, the Netherlands.ORCID 0000-0001-5941-4820
M Arfan IkramDepartment of Epidemiology, Erasmus MC-University Medical Center Rotterdam, Rotterdam, the Netherlands.ORCID 0000-0003-0372-8585
Frank J WoltersDepartment of Epidemiology, Erasmus MC-University Medical Center Rotterdam, Rotterdam, the Netherlands.ORCID 0000-0003-2226-4050
Maarten J G LeeningDepartment of Epidemiology, Erasmus MC-University Medical Center Rotterdam, Rotterdam, the Netherlands.ORCID 0000-0002-4143-4839
Evelien I T de SchepperDepartment of General Practice, Erasmus MC-University Medical Center Rotterdam, Rotterdam, the Netherlands.
Silvan LicherDepartment of Epidemiology, Erasmus MC-University Medical Center Rotterdam, Rotterdam, the Netherlands.ORCID 0000-0002-4586-4035
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuring the Coronavirus Disease 2019 (COVID-19) pandemic, the number of consultations and diagnoses in primary care and referrals to specialist care declined substantially compared to prepandemic levels. Beyond deferral of elective non-COVID-19 care by healthcare providers, it is unclear to what extent healthcare avoidance by community-dwelling individuals contributed to this decline in routine healthcare utilisation. Moreover, it is uncertain which specific symptoms were left unheeded by patients and which determinants predispose to healthcare avoidance in the general population. In this cross-sectional study, we assessed prevalence of healthcare avoidance during the pandemic from a patient perspective, including symptoms that were left unheeded, as well as determinants of healthcare avoidance. METHODS AND

findingsOn April 20, 2020, a paper COVID-19 survey addressing healthcare utilisation, socioeconomic factors, mental and physical health, medication use, and COVID-19-specific symptoms was sent out to 8,732 participants from the population-based Rotterdam Study (response rate 73%). All questionnaires were returned before July 10, 2020. By hand, prevalence of healthcare avoidance was subsequently verified through free text analysis of medical records of general practitioners. Odds ratios (ORs) for avoidance were determined using logistic regression models, adjusted for age, sex, and history of chronic diseases. We found that 1,142 of 5,656 included participants (20.2%) reported having avoided healthcare. Of those, 414 participants (36.3%) reported symptoms that potentially warranted urgent evaluation, including limb weakness (13.6%), palpitations (10.8%), and chest pain (10.2%). Determinants related to avoidance were older age (adjusted OR 1.14 [95% confidence interval (CI) 1.08 to 1.21]), female sex (1.58 [1.38 to 1.82]), low educational level (primary education versus higher vocational/university 1.21 [1.01 to 1.46), poor self-appreciated health (per level decrease 2.00 [1.80 to 2.22]), unemployment (versus employed 2.29 [1.54 to 3.39]), smoking (1.34 [1.08 to 1.65]), concern about contracting COVID-19 (per level increase 1.28 [1.19 to 1.38]) and symptoms of depression (per point increase 1.13 [1.11 to 1.14]) and anxiety (per point increase 1.16 [1.14 to 1.18]). Study limitations included uncertainty about (perceived) severity of the reported symptoms and potentially limited generalisability given the ethnically homogeneous study population.

conclusionsIn this population-based cross-sectional study, 1 in 5 individuals avoided healthcare during lockdown in the COVID-19 pandemic, often for potentially urgent symptoms. Healthcare avoidance was strongly associated with female sex, fragile self-appreciated health, and high levels of depression and anxiety. These results emphasise the need for targeted public education urging these vulnerable patients to timely seek medical care for their symptoms to mitigate major health consequences.

Indexed as

AgedAged, 80 and overAnxietyCommunicable Disease ControlCOVID-19Cross-Sectional StudiesDelivery of Health CareDepressionFemaleHealth FacilitiesHealth PersonnelHumansMaleMental HealthMiddle AgedNetherlands

Identifiers

PMID34813591
PMCPMC8610236
OpenAlexW3214836937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.