Evidence map›Paper›PMID 34813461›Full record

ArticleClinical practice and cases in emergency medicine2021

Bilateral Cranial Nerve VI Palsies in Cryptococcal Meningitis, HIV, and Syphilis: A Case Report.

Germaine Rival, Onyi Okorji, Rachael Kern, Preya Patel, Kate Fradeneck, Darragh Cullen

Open access · goldAbstract read
In one paragraph

Article in Clinical practice and cases in emergency medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Cryptococcal meningitis.Nature reviews. Disease primers · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Germaine RivalJefferson Health Northeast, Department of Emergency Medicine, Philadelphia, Pennsylvania.
Onyi OkorjiJefferson Health Northeast, Department of Emergency Medicine, Philadelphia, Pennsylvania.
Rachael KernJefferson Health Northeast, Department of Emergency Medicine, Philadelphia, Pennsylvania.
Preya PatelJefferson Health Northeast, Department of Emergency Medicine, Philadelphia, Pennsylvania.
Kate FradeneckJefferson Health Northeast, Department of Emergency Medicine, Philadelphia, Pennsylvania.
Darragh CullenJefferson Health Northeast, Department of Emergency Medicine, Philadelphia, Pennsylvania.
Jefferson College · USAria - Jefferson Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCranial nerve (CN) VI palsy is a common complaint seen in the emergency department (ED) and has a wide range of causes. Bilateral CN VI palsies are uncommon and appear to be associated with more severe complications. CASE REPORT: A 29-year-old male presented to the ED from an ophthalmology office for diplopia, headache, and strabismus. He was found to have bilateral CN VI palsies and new-onset seizure in the ED. A lumbar puncture revealed cryptococcal meningitis. Additional tests revealed a new diagnosis of human immunodeficiency virus (HIV), acquired immunodeficiency syndrome (AIDS), and syphilis.

conclusionCryptococcal meningitis remains a life-threatening complication of HIV/AIDS. Coinfections with HIV, particularly syphilis, further complicate a patient's prognosis as both can lead to devastating neurological sequelae. In cryptococcal meningitis, elevated intracranial pressure is a complication that can manifest as seizures, altered mental status, and cranial nerve palsies.

Identifiers

PMID34813461
PMCPMC8610467
OpenAlexW3208338577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.