Evidence map›Paper›PMID 34813136›Full record

ArticleTransplant infectious disease : an official journal of the Transplantation Society2022

Early steps to kidney transplantation among persons with HIV and end-stage renal disease in ESRD network 6.

Ruth O Adekunle, Aneesh K Mehta, Zhengsheng Wang, Rachel E Patzer, Rebecca Zhang

Abstract read
In one paragraph

Article in Transplant infectious disease : an official journal of the Transplantation Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. The miRNomics of antiretroviral therapy-induced obesity.Functional & integrative genomics · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruth O AdekunleDivision of Infectious Diseases, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA.ORCID https://orcid.org/0000-0001-5578-6571
Aneesh K MehtaDepartment of Biostatistics, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0002-6552-9162
Zhengsheng WangDivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Rachel E PatzerDivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0003-2573-9963
Rebecca ZhangDivision of Transplantation, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, USA.

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
J: NRSA Training CoreTL1TR002382 · NCATS · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Vasiliki Michopoulos · 2017 to 2026
$8.5M
Reducing Racial Disparities in Access to Kidney Transplantation: the RaDIANT Regional StudyU01MD010611 · NIMHD · EMORY UNIVERSITY · PI PATZER, RACHEL E · 2016 to 2020
$2.8M
Evaluation of Racial Disparities in Access to Kidney Transplantation in New National Kidney Allocation PolicyR01MD010290 · NIMHD · EMORY UNIVERSITY · PI PATZER, RACHEL E · 2015 to 2019
$2.6M
A regionally coordinated intervention to reduce racial disparities in access to kR24MD008077 · NIMHD · EMORY UNIVERSITY · PI PATZER, RACHEL E · 2013 to 2015
$916k
NCATS NIH HHS TL1 TR002382NCATS NIH HHS TL1TR002382NCATS NIH HHS UL1 TR002378NCATS NIH HHS UL1TR002378NIMHD NIH HHS R01 MD010290NIMHD NIH HHS R01MD010290NIMHD NIH HHS R24 MD008077NIMHD NIH HHS R24MD008077NIMHD NIH HHS U01 MD010611NIMHD NIH HHS U01MD010611
6 · The paper itself

Abstract

introductionEnd-stage renal disease is a significant cause of morbidity and mortality in persons with HIV (PWH). Limited data exist on access to kidney transplantation for this population.

methodsA dataset inclusive of incident dialysis patients between 2012 and 2016 with follow-up through December 2017 that identifies PWH and the general dialysis population of Network 6 (Georgia, North Carolina, South Carolina) was created through merging the United States Renal Data System with the southeastern early transplant access registry. Early steps to kidney transplantation and patient and dialysis facility-level characteristics that serve as barriers to transplantation were described.

resultsTwenty-three thousand four hundred fourteen patients were identified; 469 were PWH. Compared to non-HIV individuals, PWH were younger (49 vs. 58 years, p < 0.001), predominantly Black (87% vs. 56% p < 0.001) and male (72% vs. 56% p < 0.001). PWH were less likely to be referred to kidney transplant within 1 year of starting dialysis (36% vs. 41% p < 0.001) and waitlisted within 1 year of evaluation-start (14% vs. 30%, p = 0.05). PWH (vs. non-PWH) waited longer for referral, evaluation-start, and waitlisting and in multivariable analysis; HIV positivity was associated with a lower probability of referral (hazard ratios [HR]: 0.70; 95% confidence intervals [CIs]: 0.62-0.80), evaluation (HR 0.66; 95% CI: 0.55-0.80), and waitlisting (HR 0.29; 95% CI: 0.20-0.41).

conclusionsTargeted interventions are needed to improve access to kidney transplants, particularly in waitlisting, for PWH.

Indexed as

HIV InfectionsKidney Failure, ChronicKidney TransplantationHumansMaleReferral and ConsultationRenal DialysisUnited StatesWaiting Listsaccess to transplantdisparitieskidney transplantpersons with HIV

Identifiers

PMID34813136
PMCPMC8825692

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.