Evidence map›Paper›PMID 34812999›Full record

ArticleMolecular biology reports2022

Genes involved in mRNA surveillance are induced in Brachypodium distachyon under cadmium toxicity.

Emre Aksoy, Ali Tevfik Uncu, Ertugrul Filiz, Şule Orman, Durmuş Çetin, M Aydın Akbudak

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In one paragraph

Article in Molecular biology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Emre AksoyDepartment of Biological Sciences, Middle East Technical University, Ankara, Turkey.ORCID http://orcid.org/0000-0002-9410-2715
Ali Tevfik UncuDepartment of Molecular Biology and Genetics, Necmettin Erbakan University, Konya, Turkey.ORCID http://orcid.org/0000-0003-4729-5750
Ertugrul FilizDepartment of Agricultural Production, Duzce University, Cilimli Vocational School, Duzce, Turkey.ORCID http://orcid.org/0000-0001-9636-6389
Şule OrmanDepartment of Soil Science and Plant Nutrition, Akdeniz University, Antalya, Turkey.ORCID http://orcid.org/0000-0002-4434-2606
Durmuş ÇetinDepartment of Agricultural Biotechnology, Akdeniz University, Antalya, Turkey.ORCID http://orcid.org/0000-0001-9567-4531
M Aydın AkbudakDepartment of Agricultural Biotechnology, Akdeniz University, Antalya, Turkey. akbudak@akdeniz.edu.tr.ORCID http://orcid.org/0000-0002-1397-4678
Akdeniz University · TRDüzce Üniversitesi · TRMiddle East Technical University · TRNecmettin Erbakan University · TR

Funding

Akdeniz Üniversitesi FBA-2018-3532
6 · The paper itself

Abstract

backgroundCd accumulation in plant cells results in dramatic problems including oxidative stress and inhibition of vital enzymes. It also affects mineral uptakes by disrupting membrane permeability. Interaction among Cd and other plant nutrient elements changes the nutritional contents of crops and reduces their yield. METHODS AND

resultsIn the present study, Cd stress in Brachypodium distachyon led to the upregulation of some heavy metal transport genes (influx or efflux) encoding cation-efflux proteins, heavy metal-associated proteins and NRAMP proteins. The Arabidopsis orthologs of the differentially expressed B. distachyon genes (DEGs) under Cd toxicity were identified, which exhibited Bradi4g26905 was an ortholog of AtALY1-2. Detailed co-expression network and gene ontology analyses found the potential involvement of the mRNA surveillance pathway in Cd tolerance in B. distachyon. These genes were shown to be downregulated by sulfur (S) deficiency.

conclusionsThis is the first transcriptomic study investigating the effect of Cd toxicity in B. distachyon, a model plant for genomic studies in Poaceae (Gramineae) species. The results are expected to provide valuable information for more comprehensive research related to heavy metal toxicity in plants.

Indexed as

ArabidopsisBrachypodiumCadmiumGene Expression Regulation, PlantGenes, PlantPlant ProteinsRNA, MessengerStress, PhysiologicalCadmiumPlant ProteinsRNA, MessengerBrachypodium distachyonCadmium toxicityHeavy metal stressmRNA surveillanceRNAseq

Identifiers

PMID34812999
OpenAlexW3214997450

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.