Evidence map›Paper›PMID 34812914›Full record

ArticleHeart and vessels2022

Safety evaluation of high-risk myocardial micro-biopsy in a swine model.

Arvin Chireh, Mikael Sandell, Rikard Grankvist, Victoria Lövljung, Jonathan Al-Saadi, Fabian Arnberg, Johan Lundberg, Magnus Settergren, Staffan Holmin

Open access · hybridAbstract read
In one paragraph

Article in Heart and vessels, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Arvin ChirehDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-4763-8293
Mikael SandellDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Rikard GrankvistDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Victoria LövljungDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Jonathan Al-SaadiDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Fabian ArnbergDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Johan LundbergDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Magnus SettergrenDepartment of Cardiology, Karolinska University Hospital, Stockholm, Sweden.
Staffan HolminDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. staffan.holmin@ki.se.
Karolinska Institutet · SEKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of the study was to investigate the safety profile of high-risk micro-endomyocardial biopsy (micro-EMB) compared to conventional EMB in a large animal model. Twenty pigs were subjected to a maximum of 30 consecutive biopsies, including sampling from the free ventricular wall, with either micro-EMB (n = 10) or conventional EMB (n = 10). There were no major complications in the micro-EMB group (0/10), compared to six major complications in the EMB group (6/10; p = 0.003). Survival analysis further highlighted these differences (p = 0.004). There were significantly higher volumes of pericardial effusion in the EMB group (p = 0.01). The study shows a safety advantage of micro-EMB compared to standard EMB in the experimental high-risk circumstances investigated in this animal study. These results indicate enhanced possibilities to collect samples from sensitive areas by using the micro-EMB technique instead of standard EMB.

Indexed as

MyocardiumPericardial EffusionAnimalsBiopsyCardiac CatheterizationHeart VentriclesHumansSwineEndomyocardial biopsyInterventional cardiologyMicro-biopsySafety

Identifiers

PMID34812914
PMCPMC8917023
OpenAlexW3216842511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.