Evidence map›Paper›PMID 34812713›Full record

Trial reportPsychological medicine2023

Change in impulsivity is prospectively associated with treatment outcomes for binge-eating disorder.

Rebecca G Boswell, Ralitza Gueorguieva, Carlos M Grilo

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. An examination of state and trait urgency in individuals with binge-eating disorder.European eating disorders review : the journal of the Eating Disorders Association · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rebecca G BoswellDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.ORCID https://orcid.org/0000-0002-3062-5648
Ralitza GueorguievaDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Carlos M GriloDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Yale University · US

Funding

Treatment of Obesity and Binge Eating: Behavioral weight Loss versus Stepped CareR01DK049587 · NIDDK · YALE UNIVERSITY · PI GRILO, CARLOS M · 2002 to 2020
$8.5M
Efficacy and Mechanisms of Naltrexone+Bupropion for Binge Eating DisorderR01DK112771 · NIDDK · YALE UNIVERSITY · PI GRILO, CARLOS M, MCKEE, SHERRY ANN · 2017 to 2021
$3.6M
Cognitive-Behavioral and Pharmacologic Treatment of Binge Eating DisorderR01DK114075 · NIDDK · YALE UNIVERSITY · PI GRILO, CARLOS M · 2018 to 2022
$3.6M
Neurocognitive fMRI Mechanisms of CBT and Lisdexamfetamine Outcomes in Obesity and BEDR01DK121551 · NIDDK · YALE UNIVERSITY · PI GRILO, CARLOS M, POTENZA, MARC N · 2019 to 2023
$1.8M
NIDDK NIH HHS R01 DK049587NIDDK NIH HHS R01 DK112771NIDDK NIH HHS R01 DK114075NIDDK NIH HHS R01 DK121551
6 · The paper itself

Abstract

backgroundImpulsivity may be a process underlying binge-eating disorder (BED) psychopathology and its treatment. This study examined change in impulsivity during cognitive-behavioral therapy (CBT) and/or pharmacological treatment for BED and associations with treatment outcomes.

methodsIn total, 108 patients with BED (

resultsImpulsivity declined significantly throughout treatment and follow-up across treatment groups. Rapid change in impulsivity and overall change in impulsivity during treatment were significantly associated with reductions in eating-disorder psychopathology, depression scores, and BMI during treatment and at post-treatment. Overall change in impulsivity during treatment was associated with subsequent reductions in depression scores at 12-month follow-up. Baseline impulsivity did not moderate/predict eating-disorder outcomes or BMI but did predict change in depression scores.

conclusionsRapid and overall reductions in impulsivity during treatment were associated with improvements in specific eating-disorder psychopathology and associated general outcomes. These effects were found for both CBT and pharmacological treatment for BED. Change in impulsivity may be an important process prospectively related to treatment outcome.

Indexed as

Binge-Eating DisorderCognitive Behavioral TherapyHumansImpulsive BehaviorObesityTreatment OutcomeBinge-eating disordercognitive-behavioral therapyeating disordersfluoxetineimpulsivityobesitytreatment

Identifiers

PMID34812713
PMCPMC9124732
OpenAlexW3216377339

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.