Evidence map›Paper›PMID 34812407›Full record

ArticleBioMed research international2021

Identification of Peptides as Novel Inhibitors to Target IFN-

Ghulam Mustafa, Hafiza Salaha Mahrosh, Mahwish Salman, Sumaira Sharif, Raheela Jabeen, Tanveer Majeed, Hafsah Tahir

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Cytokines inhibitory mechanism ofIn silico pharmacology · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Exploring the antihyperglycemic potential of tetrapeptides devised from AdMc1International journal of immunopathology and pharmacology
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Ghulam MustafaDepartment of Biochemistry, Government College University, Faisalabad, 38000, Pakistan.ORCID https://orcid.org/0000-0001-6510-6496
Hafiza Salaha MahroshDepartment of Biochemistry, Government College University, Faisalabad, 38000, Pakistan.ORCID https://orcid.org/0000-0002-6664-1543
Mahwish SalmanDepartment of Biochemistry, Government College University, Faisalabad, 38000, Pakistan.
Sumaira SharifInstitute of Molecular Biology and Biotechnology, The University of Lahore, Pakistan.ORCID https://orcid.org/0000-0002-6277-2562
Raheela JabeenDepartment of Biochemistry and Biotechnology, The Women University Multan, Pakistan.
Tanveer MajeedDepartment of Biotechnology, Kinnaird College for Women, Lahore, Pakistan.
Hafsah TahirDepartment of Environmental Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
Government College University, Faisalabad · PKKinnaird College for Women University · PKQuaid-i-Azam University · PKThe Women University Multan · PKUniversity of Lahore · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune disorder is a chronic immune imbalance which is developed through a series of pathways. The defect in B cells, T cells, and lack of self-tolerance has been greatly associated with the onset of many types of autoimmune complications including rheumatoid arthritis, systemic lupus erythematosus (SLE), multiple sclerosis, and chronic inflammatory demyelinating polyneuropathy. The SLE is an autoimmune disease with a common type of lupus that causes tissue and organ damage due to the wide spread of inflammation. In the current study, twenty anti-inflammatory peptides derived from plant and animal sources were docked as ligands or peptides counter to proinflammatory cytokines. Interferon gamma (IFN-

Indexed as

Amino Acid SequenceAnimalsAnti-Inflammatory AgentsDrug DiscoveryHumansInterferon-gammaInterleukin-3LigandsLupus Erythematosus, SystemicMolecular Docking SimulationMolecular Dynamics SimulationOligopeptidesPlant ProteinsTumor Necrosis Factor-alphaAnti-Inflammatory AgentsInterferon-gammaInterleukin-3LigandsOligopeptidesPlant ProteinsTumor Necrosis Factor-alpha

Identifiers

PMID34812407
PMCPMC8605925
OpenAlexW3212878909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.