Evidence map›Paper›PMID 34811862›Full record

ReviewDermatologic therapy2022

COVID vaccination in patients under treatment with rituximab: A presentation of two cases from Iran and a review of the current knowledge with a specific focus on pemphigus.

Parvaneh Hatami, Kamran Balighi, Hamed Nicknam Asl, Zeinab Aryanian

Open access · bronzeAbstract readReview
In one paragraph

Review in Dermatologic therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Parvaneh HatamiAutoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-3531-2907
Kamran BalighiAutoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-8059-670X
Hamed Nicknam AslDepartment of Dentistry, Rafsanjan University of Medical Sciences (RUMS), Rafsanjan, Iran.
Zeinab AryanianAutoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0001-7077-1458
Tehran University of Medical Sciences · IRRafsanjan University of Medical Sciences · IRRazi Hospital · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-COV2 vaccines were approved without long-term monitoring due to emergent situations. This has raised some issues about the timing and protocol of receiving vaccines in specific situations such as patients receiving immunomodulatory agents including rituximab, which is widely used for various disorders such as multiple sclerosis, pemphigus, and many rheumatologic disorders. We described two cases of pemphigus vulgaris (a new case and one with flare-up) following vaccination with Astrazeneca in Iran and reviewed the existing data in this regard through searching on PubMed, Google Scholar, and Scopus. All of the relevant papers published until June 28, 2021, which we could access their full-texts were included. We found some recommendations made by rheumatologists, neurologists, and dermatologists in regard to vaccination timing in this group of patients and tried to summarize them to provide a practical guide for clinicians. Clinicians should perform a careful, individualized risk-benefit assessment for their patients and consider a delay in rituximab administration after completion of COVID vaccination if there is not any considerable risk of disease relapse or organ failure. Moreover, choosing vaccines with potential of providing protection after single dose, especially in countries with limited access to vaccines may be a reasonable approach.

Indexed as

COVID-19PemphigusCOVID-19 VaccinesHumansImmunomodulating AgentsIranRituximabRNA, ViralSARS-CoV-2VaccinationCOVID-19 VaccinesImmunomodulating AgentsRituximabRNA, ViralAstrazenecaBharatCOVID-19 vaccineModernaPfizerSputnik

Identifiers

PMID34811862
PMCPMC9011959
OpenAlexW3216899441

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.