Evidence map›Paper›PMID 34811740›Full record

ArticleBritish journal of pharmacology2022

Delineating the interactions between the cannabinoid CB

Monica Patel, Christoph Matti, Natasha L Grimsey, Daniel F Legler, Jonathan A Javitch, David B Finlay, Michelle Glass

Open access · bronzeAbstract read
In one paragraph

Article in British journal of pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Cannabinoid CBBritish journal of pharmacology · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Mechanisms of cannabinoid tolerance.Biochemical pharmacology · 2023
    Review
  10. Cannabinoid 1 (CBBritish journal of pharmacology · 2023
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Monica PatelDepartment of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.ORCID 0000-0003-2686-7246
Christoph MattiDepartment of Biology, Biotechnology Institute Thurgau (BITg) at the University of Konstanz, Kreuzlingen, Switzerland.ORCID 0000-0002-6728-9449
Natasha L GrimseyDepartment of Pharmacology and Clinical Pharmacology, School of Medical Sciences, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.ORCID 0000-0003-3941-4537
Daniel F LeglerDepartment of Biology, Biotechnology Institute Thurgau (BITg) at the University of Konstanz, Kreuzlingen, Switzerland.ORCID 0000-0001-8610-4764
Jonathan A JavitchDepartment of Psychiatry and Pharmacology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.ORCID 0000-0001-7395-2967
David B FinlayDepartment of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.ORCID 0000-0002-3160-2931
Michelle GlassDepartment of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.ORCID 0000-0002-5997-6898
University of Otago · NZBiotechnology Institute Thurgau · CHNew York Psychoanalytic Society and Institute · USUniversity of Auckland · NZUniversity of Bern · CH

Funding

Structure of the Dopamine D2-Like Receptor Binding SitesR01MH054137 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI JAVITCH, JONATHAN A · 1995 to 2025
$12.0M
NIMH NIH HHS R01 MH054137
6 · The paper itself

Abstract

background and purposeThe cannabinoid CB EXPERIMENTAL APPROACH: In CB KEY

resultsOverexpression of GRK isoforms 1-6 failed to considerably improve translocation of either β-arrestin 1 or β-arrestin 2 to CB CONCLUSION AND IMPLICATIONS: Our findings suggest that CB

Indexed as

beta-Arrestin 2CannabinoidsG-Protein-Coupled Receptor KinasesReceptor, Cannabinoid, CB2beta-ArrestinsHEK293 CellsHumansPhosphorylationbeta-Arrestin 2beta-ArrestinsCannabinoidsG-Protein-Coupled Receptor KinasesReceptor, Cannabinoid, CB2cannabinoid CB2 receptorGPCR kinaseβ-arrestin

Identifiers

PMID34811740
PMCPMC12591375
OpenAlexW3215103241

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.