Evidence map›Paper›PMID 34811707›Full record

ArticleCognitive, affective & behavioral neuroscience2022

μ-opioid receptor availability is associated with sex drive in human males.

Lauri Nummenmaa, Patrick Jern, Tuulia Malén, Tatu Kantonen, Laura Pekkarinen, Lasse Lukkarinen, Lihua Sun, Pirjo Nuutila, Vesa Putkinen

Open access · hybridAbstract read
In one paragraph

Article in Cognitive, affective & behavioral neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Aberrant type 2 dopamine and mu-opioid receptor availability in autism spectrum disorder.European journal of nuclear medicine and molecular imaging · 2026
    Article
  3. Article
  4. Endogenous Opioid Release After Orgasm in Man: A Combined PET/Functional MRI Study.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Lauri NummenmaaTurku Pet Centre and Turku University Hospital, FI-20520, Turku, Finland. latanu@utu.fi.
Patrick JernDepartment of Psychology, Åbo Akademi University, Turku, Finland.ORCID 0000-0001-9044-7604
Tuulia MalénTurku Pet Centre and Turku University Hospital, FI-20520, Turku, Finland.
Tatu KantonenTurku Pet Centre and Turku University Hospital, FI-20520, Turku, Finland.
Laura PekkarinenTurku Pet Centre and Turku University Hospital, FI-20520, Turku, Finland.ORCID 0000-0002-5596-0485
Lasse LukkarinenTurku Pet Centre and Turku University Hospital, FI-20520, Turku, Finland.
Lihua SunTurku Pet Centre and Turku University Hospital, FI-20520, Turku, Finland.
Pirjo NuutilaTurku Pet Centre and Turku University Hospital, FI-20520, Turku, Finland.
Vesa PutkinenTurku Pet Centre and Turku University Hospital, FI-20520, Turku, Finland.
Turku University Hospital · FIUniversity of Turku · FIÅbo Akademi University · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endogenous mu-opioid receptor (MOR) system modulates a multitude of social and reward-related functions, and exogenous opiates also influence sex drive in humans and animals. Sex drive shows substantial variation across humans, and it is possible that individual differences in MOR availability underlie interindividual of variation in human sex drive. We measured healthy male subjects' (n = 52) brain's MOR availability with positron emission tomography (PET) using an agonist radioligand, [

Indexed as

BrainPositron-Emission TomographyAnimalsBayes TheoremHumansIndividualityMaleRewardNeurotransmissionOpioidsPETSex driveVBM

Identifiers

PMID34811707
PMCPMC8983533
OpenAlexW3215974151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.