Evidence map›Paper›PMID 34811586›Full record

ArticleWorld journal of urology2022

Computational fluid dynamics modeling approaches to assess lower urinary tract hydraulic dynamics in posterior urethral valve before and after endoscopic valve ablation: a pilot study.

Hong-Song Chen, Xing Liu, Zhi-Cheng Zhang, Zi-Han Ye, Tao Lin, Da-Wei He, Guang-Hui Wei

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Article in World journal of urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hong-Song ChenDepartment of Urology, Children's Hospital of Chongqing Medical University, Chongqing, 400014, PR China.
Xing LiuDepartment of Urology, Children's Hospital of Chongqing Medical University, Chongqing, 400014, PR China. dr.liux0217@gmail.com.
Zhi-Cheng ZhangDepartment of Urology, Children's Hospital of Chongqing Medical University, Chongqing, 400014, PR China.
Zi-Han YeDepartment of Urology, Children's Hospital of Chongqing Medical University, Chongqing, 400014, PR China.
Tao LinDepartment of Urology, Children's Hospital of Chongqing Medical University, Chongqing, 400014, PR China.
Da-Wei HeDepartment of Urology, Children's Hospital of Chongqing Medical University, Chongqing, 400014, PR China.
Guang-Hui WeiDepartment of Urology, Children's Hospital of Chongqing Medical University, Chongqing, 400014, PR China.
Children's Hospital of Chongqing Medical University · CNChina International Science and Technology Cooperation · CNChongqing Medical University · CN

Funding

National Natural Science Foundation of China 81970571
6 · The paper itself

Abstract

purposeComputational fluid dynamics (CFD) has been used successfully in cardiovascular system research to analyze the physiological processes inside vessels. We evaluated the hydraulic information of urine through the lower urinary tract in a patient with posterior urethral valve (PUV) before and after valve ablation by CFD.

methodsA set of models of the lower urinary tract were developed based on geometrical data obtained by cystoscopy and voiding cystourethrography. Simulated assumptions and conditions were applied according to prior studies and urodynamic results. We used Fluent CFD 19.0 (Ansys Inc., USA) to compute the velocity and pressure of the fluid regions. The simplification of Bernoulli's formula was applied afterward to calculate the hydraulic energy of different positions.

resultsThe urine flow rates of the NORMALst, the PUVst, and the POSTst at 5000 Pa were 18.08 ml/s, 11.14 ml/s, and 12.16 ml/s, respectively. Precipitous pressure change was observed around the valve in the PUVst, and the abnormal change was concentrated in the dilated urethra in the POSTst. Major energy dissipations were generated around the valve and the dilated urethra in the PUVst. The energy loss that occurred in the dilated urethra did not improve after the operation.

conclusionsOur findings are probably indicative of the hydrodynamics changes in the dilated urethra in PUV and need to be confirmed through more improved CFD models in the future. CFD may revolutionize pediatric urologists' perception in the management of urinary disease.

Indexed as

HydrodynamicsUrethral ObstructionChildHumansMalePilot ProjectsRetrospective StudiesUrethraHydrodynamicsMedical informatics computingPatient-specific modelingPediatricsUrethral obstruction

Identifiers

PMID34811586
OpenAlexW3215757589

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.