Evidence map›Paper›PMID 34811433›Full record

Trial reportScientific reports2021

Bimanual digit training improves right-hand dexterity in older adults by reactivating declined ipsilateral motor-cortical inhibition.

Eiichi Naito, Tomoyo Morita, Satoshi Hirose, Nodoka Kimura, Hideya Okamoto, Chikako Kamimukai, Minoru Asada

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

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  16. Effects of home-based manual dexterity training on cognitive function among older adults: a randomized controlled trial.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2023
    Article
  17. Finger dexterity measured by the Grooved Pegboard test indexes Parkinson's motor severity in a tremor-independent manner.Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Eiichi NaitoCenter for Information and Neural Networks (CiNet), Advanced ICT Research Institute, National Institute of Information and Communications Technology (NICT), 1-4 Yamadaoka, Suita, Osaka, 565-0871, Japan. eiichi.naito@nict.go.jp.
Tomoyo MoritaCenter for Information and Neural Networks (CiNet), Advanced ICT Research Institute, National Institute of Information and Communications Technology (NICT), 1-4 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Satoshi HiroseCenter for Information and Neural Networks (CiNet), Advanced ICT Research Institute, National Institute of Information and Communications Technology (NICT), 1-4 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Nodoka KimuraCenter for Information and Neural Networks (CiNet), Advanced ICT Research Institute, National Institute of Information and Communications Technology (NICT), 1-4 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Hideya OkamotoElement Technology Research & Development Section, Global Research & Development Department, , Mizuno Corporation, 1-12-35 Nanko-kita, Suminoe-ku, Osaka, Osaka, 559-8510, Japan.
Chikako KamimukaiElement Technology Research & Development Section, Global Research & Development Department, , Mizuno Corporation, 1-12-35 Nanko-kita, Suminoe-ku, Osaka, Osaka, 559-8510, Japan.
Minoru AsadaCenter for Information and Neural Networks (CiNet), Advanced ICT Research Institute, National Institute of Information and Communications Technology (NICT), 1-4 Yamadaoka, Suita, Osaka, 565-0871, Japan.
National Institute of Information and Communications Technology · JPOsaka University · JP

Funding

Japan Society for the Promotion of Science JP19H05723Japan Society for the Promotion of Science JP19K22833Japan Society for the Promotion of Science JP20H04492
6 · The paper itself

Abstract

Improving deteriorated sensorimotor functions in older individuals is a social necessity in a super-aging society. Previous studies suggested that the declined interhemispheric sensorimotor inhibition observed in older adults is associated with their deteriorated hand/finger dexterity. Here, we examined whether bimanual digit exercises, which can train the interhemispheric inhibitory system, improve deteriorated hand/finger dexterity in older adults. Forty-eight healthy, right-handed, older adults (65-78 years old) were divided into two groups, i.e., the bimanual (BM) digit training and right-hand (RH) training groups, and intensive daily training was performed for 2 months. Before and after the training, we evaluated individual right hand/finger dexterity using a peg task, and the individual state of interhemispheric sensorimotor inhibition by analyzing ipsilateral sensorimotor deactivation via functional magnetic resonance imaging when participants experienced a kinesthetic illusory movement of the right-hand without performing any motor tasks. Before training, the degree of reduction/loss of ipsilateral motor-cortical deactivation was associated with dexterity deterioration. After training, the dexterity improved only in the BM group, and the dexterity improvement was correlated with reduction in ipsilateral motor-cortical activity. The capability of the brain to inhibit ipsilateral motor-cortical activity during a simple right-hand sensory-motor task is tightly related to right-hand dexterity in older adults.

Indexed as

Inhibition, PsychologicalAdultAgedAgingBrain MappingExerciseFemaleFingersFunctional LateralityHumansMagnetic Resonance ImagingMaleMotor CortexMotor SkillsMovementSingle-Blind Method

Identifiers

PMID34811433
PMCPMC8608823
OpenAlexW3217675823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.