Evidence map›Paper›PMID 34811422›Full record

ArticleScientific reports2021

The impact of lockdown stress and loneliness during the COVID-19 pandemic on mental health among university students in Germany.

Antonia M Werner, Ana N Tibubos, Lina M Mülder, Jennifer L Reichel, Markus Schäfer, Sebastian Heller, Daniel Pfirrmann, Dennis Edelmann, Pavel Dietz, Thomas Rigotti and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  6. Stress and Resilience Development in German Dental Students.European journal of dental education : official journal of the Association for Dental Education in Europe · 2026
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Antonia M WernerDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Untere Zahlbacher Str. 8, 55131, Mainz, Germany. Antonia.Werner@unimedizin-mainz.de.ORCID 0000-0002-4150-354X
Ana N TibubosDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Untere Zahlbacher Str. 8, 55131, Mainz, Germany.ORCID 0000-0003-4284-0019
Lina M MülderDepartment of Work, Organizational and Business Psychology, Institute of Psychology, Johannes Gutenberg University Mainz, Mainz, Germany.
Jennifer L ReichelInstitute of Occupational, Social and Environmental Medicine, University Medical Center of the University of Mainz, Mainz, Germany.
Markus SchäferDepartment of Communication, Johannes Gutenberg University Mainz, Mainz, Germany.
Sebastian HellerInstitute of Occupational, Social and Environmental Medicine, University Medical Center of the University of Mainz, Mainz, Germany.
Daniel PfirrmannDepartment of Sports Medicine, Rehabilitation and Disease Prevention, Institute of Sport Science, Johannes Gutenberg University Mainz, Mainz, Germany.
Dennis EdelmannDepartment of Sports Medicine, Rehabilitation and Disease Prevention, Institute of Sport Science, Johannes Gutenberg University Mainz, Mainz, Germany.
Pavel DietzInstitute of Occupational, Social and Environmental Medicine, University Medical Center of the University of Mainz, Mainz, Germany.
Thomas RigottiDepartment of Work, Organizational and Business Psychology, Institute of Psychology, Johannes Gutenberg University Mainz, Mainz, Germany.ORCID 0000-0001-9189-0018
Manfred E BeutelDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Untere Zahlbacher Str. 8, 55131, Mainz, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic led to a shutdown of universities in Germany. In a longitudinal design, we compared mental health (depression, anxiety, somatic complaints) of university students in Germany before (June to August 2019) and in the course of the COVID-19 pandemic (June 2020) and determined the impact of pandemic-related stress and loneliness on students' mental health in self-report online surveys. We investigated 443 participants (mean age 22.8 years), among them 77% female, and 10.4% medical students. A small increase of depression mean scores was observed (F(1,420) = 5.21; p = .023), anxiety and somatic complaints have not significantly changed. There was a medium increase in loneliness from pre-pandemic scores to the pandemic situation (F(1,423) = 30.56; p < .001). Analyzed with regression analyses, current loneliness and pre-pandemic distress represented the strongest associations with mental health during the pandemic. Additionally, health-related concerns during the pandemic were associated with symptoms of depression [b = 0.21; 95%CI(0.08; 0.34); t = 3.12; p = .002], anxiety [b = 0.07; 95%CI(0.01; 0.12); t = 2.50; p = .013], somatic complaints [b = 0.33; 95%CI(0.18; 0.47); t = 4.49; p < .001], and loneliness [b = 0.10; 95%CI(0.03; 0.17); t = 2.74; p = .006]. Social stress due to the pandemic situation was associated with loneliness [b = 0.38; 95%CI(0.32; 0.45); t = 11.75; p < .001]. The results imply that university students represent a risk group for psychosocial long-term ramifications of the pandemic.

Indexed as

Stress, PsychologicalAdultAnxietyCOVID-19DepressionFemaleGermanyHumansLonelinessLongitudinal StudiesMaleMental HealthPandemicsQuarantineSelf ReportSex Distribution

Identifiers

PMID34811422
PMCPMC8609027

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.