Evidence map›Paper›PMID 34810277›Full record

ArticleOpen heart2021

Impact of cancer on short-term in-hospital mortality after primary acute myocardial infarction.

Robert Zheng, Kenya Kusunose, Yuichiro Okushi, Yoshihiro Okayama, Michikazu Nakai, Yoko Sumita, Takayuki Ise, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda and 4 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Open heart, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Robert ZhengDepartment of Cardiovascular Medicine, Tokushima University Hospital, Tokushima, Japan.
Kenya KusunoseDepartment of Cardiovascular Medicine, Tokushima University Hospital, Tokushima, Japan kusunosek@tokushima-u.ac.jp.ORCID 0000-0002-4909-754X
Yuichiro OkushiDepartment of Cardiovascular Medicine, Tokushima University Hospital, Tokushima, Japan.
Yoshihiro OkayamaDepartment of Cardiovascular Medicine, Tokushima University Hospital, Tokushima, Japan.
Michikazu NakaiCenter for Cerebral and Cardiovascular Disease Information, National Cerebral and Cardiovascular Center, Osaka, Japan.
Yoko SumitaCenter for Cerebral and Cardiovascular Disease Information, National Cerebral and Cardiovascular Center, Osaka, Japan.
Takayuki IseDepartment of Cardiovascular Medicine, Tokushima University Hospital, Tokushima, Japan.
Koji YamaguchiDepartment of Cardiovascular Medicine, Tokushima University Hospital, Tokushima, Japan.
Shusuke YagiDepartment of Cardiovascular Medicine, Tokushima University Hospital, Tokushima, Japan.
Daiju FukudaDepartment of Cardiovascular Medicine, Tokushima University Hospital, Tokushima, Japan.
Hirotsugu YamadaDepartment of Community Medicine for Cardiology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.ORCID 0000-0003-3741-5560
Takeshi SoekiDepartment of Cardiovascular Medicine, Tokushima University Hospital, Tokushima, Japan.
Tetsuzo WakatsukiDepartment of Cardiovascular Medicine, Tokushima University Hospital, Tokushima, Japan.
Masataka SataDepartment of Cardiovascular Medicine, Tokushima University Hospital, Tokushima, Japan.
Tokushima University Hospital · JPNational Cerebral and Cardiovascular Center · JPTokushima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiovascular diseases are the second most common cause of mortality among cancer survivors, after death from cancer. We sought to assess the impact of cancer on the short-term outcomes of acute myocardial infarction (AMI), by analysing data obtained from a large-scale database.

methodsThis study was based on the Diagnosis Procedure Combination database in the Japanese Registry of All Cardiac and Vascular Diseases and the Diagnosis Procedure Combination. We identified patients who were hospitalised for primary AMI between April 2012 and March 2017. Propensity Score (PS) was estimated with logistic regression model, with cancer as the dependent variable and 21 clinically relevant covariates. The main outcome was in-hospital mortality.

resultsWe split 1 52 208 patients into two groups with or without cancer. Patients with cancer tended to be older (cancer group 73±11 years vs non-cancer group 68±13 years) and had smaller body mass index (cancer group 22.8±3.6 vs non-cancer 23.9±4.3). More patients in the non-cancer group had hypertension or dyslipidaemia than their cancer group counterparts. The non-cancer group also had a higher rate of percutaneous coronary intervention (cancer 92.6% vs non-cancer 95.2%). Patients with cancer had a higher 30-day mortality (cancer 6.0% vs non-cancer 5.3%) and total mortality (cancer 8.1% vs non-cancer 6.1%) rate, but this was statistically insignificant after PS matching.

conclusionCancer did not significantly impact short-term in-hospital mortality rates after hospitalisation for primary AMI.

Indexed as

Propensity ScoreRegistriesAdultAgedAged, 80 and overFemaleFollow-Up StudiesHospital MortalityHumansJapanMaleMiddle AgedMyocardial InfarctionNeoplasmsRetrospective StudiesRisk Assessmentacute coronary syndromemyocardial infarctionrisk factors

Identifiers

PMID34810277
PMCPMC8609927
OpenAlexW3217569225

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.