Evidence map›Paper›PMID 34810220›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2022

A Soluble PrP

Elisabetta Mantuano, Pardis Azmoon, Michael A Banki, Christina J Sigurdson, Wendy M Campana, Steven L Gonias

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. New Light on Prions: Putative Role of PrPInternational journal of molecular sciences · 2024
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Elisabetta MantuanoDepartment of Pathology, University of California San Diego, La Jolla, CA; emantuano@health.ucsd.edu sgonias@health.ucsd.edu.ORCID 0000-0001-5728-9261
Pardis AzmoonDepartment of Pathology, University of California San Diego, La Jolla, CA.ORCID 0000-0002-1512-5581
Michael A BankiDepartment of Pathology, University of California San Diego, La Jolla, CA.
Christina J SigurdsonDepartment of Pathology, University of California San Diego, La Jolla, CA.
Wendy M CampanaDepartment of Anesthesiology and Program in Neurosciences, University of California San Diego, La Jolla, CA; and.
Steven L GoniasDepartment of Pathology, University of California San Diego, La Jolla, CA; emantuano@health.ucsd.edu sgonias@health.ucsd.edu.ORCID 0000-0003-0843-4607
University of California San Diego · US

Funding

Mechanisms of Prion Aggregation and Species BarriersR01NS069566 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ESKO, JEFFREY D, RAVITS, JOHN · 2011 to 2025
$5.7M
Regulation of Inflammation by the Fibrinolytic SystemR01HL136395 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GONIAS, STEVEN L. · 2017 to 2025
$3.5M
Mechanisms of Prion SpreadR01NS076896 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SIGURDSON, CHRISTINA · 2012 to 2021
$3.4M
Mechanisms of Prion Spread and Neuronal ToxicityR37NS076896 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Christina Sigurdson · 2023 to 2026
$2.6M
Molecular basis of prion protein-induced neurodegenerationRF1NS121992 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SIGURDSON, CHRISTINA · 2021 to 2023
$1.7M
Molecular basis of prion protein-induced neurodegenerationR01NS121992 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SIGURDSON, CHRISTINA · 2024 to 2025
$963k
NHLBI NIH HHS R01 HL136395NINDS NIH HHS R01 NS069566NINDS NIH HHS R01 NS076896NINDS NIH HHS R01 NS121992NINDS NIH HHS R37 NS076896NINDS NIH HHS RF1 NS121992
6 · The paper itself

Abstract

Nonpathogenic cellular prion protein (PrP

Indexed as

AnimalsCell MembraneCells, CulturedExtracellular VesiclesHumansImmunity, InnateInflammationLipopolysaccharidesLow Density Lipoprotein Receptor-Related Protein-1MacrophagesMiceMice, Inbred C57BLMice, KnockoutMultiprotein ComplexesPrPC ProteinsReceptors, N-Methyl-D-AspartateLipopolysaccharidesLow Density Lipoprotein Receptor-Related Protein-1LRP1 protein, humanMultiprotein ComplexesPrPC ProteinsReceptors, N-Methyl-D-AspartateReceptors, Pattern Recognition

Identifiers

PMID34810220
PMCPMC8702456
OpenAlexW3216417421

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.