Evidence map›Paper›PMID 34810207›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2022

Sun Exposure Is Associated with Reduced Breast Cancer Risk among Women Living in the Caribbean: The Atabey Study in Puerto Rico.

Cruz M Nazario, Rosa V Rosario-Rosado, Michelle Schelske-Santos, Imar Mansilla-Rivera, Farah A Ramírez-Marrero, Jing Nie, Paola Piovanetti-Fiol, Johan Hernández-Santiago, Jo L Freudenheim

Open access · bronzeAbstract read
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Cruz M NazarioDepartment of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico, San Juan, Puerto Rico. cruz.nazario@upr.edu.ORCID 0000-0002-5753-4738
Rosa V Rosario-RosadoDepartment of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico, San Juan, Puerto Rico.ORCID 0000-0002-1124-0400
Michelle Schelske-SantosNutrition and Dietetics Program, Río Piedras Campus, University of Puerto Rico, San Juan, Puerto Rico.
Imar Mansilla-RiveraDepartment of Environmental Health, Graduate School of Public Health, University of Puerto Rico, San Juan, Puerto Rico.
Farah A Ramírez-MarreroDepartment of Exercise Physiology, Río Piedras Campus, University of Puerto Rico, San Juan, Puerto Rico.
Jing NieDepartment of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo, New York.
Paola Piovanetti-FiolDepartment of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico, San Juan, Puerto Rico.
Johan Hernández-SantiagoDepartment of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico, San Juan, Puerto Rico.
Jo L FreudenheimDepartment of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo, New York.ORCID 0000-0002-9301-0499
University of Puerto Rico, Medical Sciences Campus · PRUniversity at Buffalo, State University of New York · USUniversity of Puerto Rico at Río Piedras · PRUniversity of Puerto Rico System · PR

Funding

TECHNOLOGIES AND RESOURCES FOR CORE LABORATORIESU54MD007587 · NIMHD · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI LUCIANO, CARLOS A., RIVERA, ADELMA · 2012 to 2018
$23.2M
Tracking and Evaluation CoreU54GM133807 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI PORTER, JAMES T. · 2020 to 2024
$17.7M
NIGMS NIH HHS U54 GM133807NIMHD NIH HHS U54 MD007587
6 · The paper itself

Abstract

backgroundThough inconsistent, there is evidence that sun exposure is associated with reduced breast cancer risk. Previous studies have been conducted in geographical regions with seasonal variation in UV radiation, including periods of low to no exposure, and among participants mostly of European descent. Puerto Rico has no significant seasonal fluctuation, with continuous exposure to very high UV radiation.

methodsWe conducted a population-based case-control study of breast cancer among women in metropolitan San Juan, Puerto Rico, examining a cumulative sun exposure index (SEI) based on a comparison of reflectance of sun-exposed and non-exposed skin. A chromameter was used to measure skin reflectance and estimate the difference between constitutive (unexposed) and facultative (exposed) skin pigmentation in 307 cases and 328 controls. Breast cancer risk factors were ascertained with interviewer-administered questionnaires. OR and 95% confidence intervals (CI) were estimated with unconditional logistic regression.

resultsAdjusted breast cancer odds were lower for the highest tertile of the SEI (OR

conclusionsWe found lower risk of breast cancer associated with greater sun exposure in a population living with high, continuous sun exposure. This beneficial finding should be placed in the context of other effects of sun exposure. IMPACT: Sun exposure is a modifiable factor that may contribute, directly or indirectly, to lower breast cancer risk.

Indexed as

SunlightAdultAgedBreast NeoplasmsCase-Control StudiesFemaleHumansMiddle AgedPuerto RicoRisk Assessment

Identifiers

PMID34810207
PMCPMC9190767
OpenAlexW3216871860

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.