Evidence map›Paper›PMID 34810198›Full record

ArticleCancer research2022

BAFF Attenuates Immunosuppressive Monocytes in the Melanoma Tumor Microenvironment.

Wei Liu, Paweł Stachura, Haifeng C Xu, Renáta Váraljai, Prashant Shinde, Nikkitha Umesh Ganesh, Matthias Mack, Anke Van Lierop, Anfei Huang, Balamurugan Sundaram and 10 more

Open access · bronzeAbstract read
In one paragraph

Article in Cancer research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  10. Article
  11. Article
  12. Innate Immune Cells in Melanoma: Implications for Immunotherapy.International journal of molecular sciences · 2024
    Review
  13. Review
  14. Article
  15. Article
  16. Article
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  18. HOOK1 Inhibits the Progression of Renal Cell Carcinoma via TGF-β and TNFSF13B/VEGF-A Axis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 1 country.

Wei LiuDepartment of Molecular Medicine II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Paweł StachuraDepartment of Molecular Medicine II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Haifeng C XuDepartment of Molecular Medicine II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Renáta VáraljaiDepartment of Dermatology, University Hospital Essen, West German Cancer Center, University of Duisburg-Essen and the German Cancer Consortium (DKTK), Essen, Germany.ORCID 0000-0001-6852-6859
Prashant ShindeDepartment of Molecular Medicine II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Nikkitha Umesh GaneshDepartment of Molecular Medicine II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.ORCID 0000-0002-9004-5960
Matthias MackDepartment of Nephrology, Universitätsklinikum Regensburg, Regensburg, Germany.
Anke Van LieropDepartment of Dermatology, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.ORCID 0000-0002-0382-6137
Anfei HuangDepartment of Molecular Medicine II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Balamurugan SundaramDepartment of Molecular Medicine II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Karl S LangInstitute of Immunology, Medical Faculty, University of Duisburg-Essen, Essen, Germany.
Daniel PicardDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany.ORCID 0000-0003-3375-6202
Ute FischerDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany.ORCID 0000-0002-2455-2489
Marc RemkeDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany.
Bernhard HomeyDepartment of Dermatology, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Alexander RoeschDepartment of Dermatology, University Hospital Essen, West German Cancer Center, University of Duisburg-Essen and the German Cancer Consortium (DKTK), Essen, Germany.
Dieter HäussingerDepartment of Gastroenterology, Hepatology, and Infectious Diseases, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.ORCID 0000-0002-5936-682X
Philipp A Lang
Arndt BorkhardtDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany.
Aleksandra A PandyraDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Center of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany. aleksandra.pandyra@uni-duesseldorf.de.
Heinrich Heine University Düsseldorf · DEGerman Cancer Research Center · DEWest German Heart and Vascular Center Essen · DEUniversity Hospital Regensburg · DEUniversity of Duisburg-Essen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging evidence indicates B-cell activating factor (BAFF,

Indexed as

Adaptive ImmunityAnimalsB-Cell Activating FactorB-Cell Activation Factor ReceptorHEK293 CellsHumansImmune ToleranceMelanoma, ExperimentalMiceMice, Inbred C57BLMonocytesSkin NeoplasmsTransfectionTumor MicroenvironmentB-Cell Activating FactorB-Cell Activation Factor ReceptorTnfrsf13c protein, mouseTNFSF13B protein, humanTnfsf13b protein, mouse

Identifiers

PMID34810198
PMCPMC9397630
OpenAlexW3214867875

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.