Evidence map›Paper›PMID 34810081›Full record

ReviewTrends in biochemical sciences2022

NAADP-binding proteins find their identity.

Jonathan S Marchant, Gihan S Gunaratne, Xinjiang Cai, James T Slama, Sandip Patel

Open access · greenAbstract readReview
In one paragraph

Review in Trends in biochemical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 27 citations in OpenAlex.

  1. Allosteric switching of CaThe EMBO journal · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. CaBiophysics reports · 2024
    Article
  9. Article
  10. The ion channels of endomembranes.Physiological reviews · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Convergent activation of CaScience signaling · 2023
    Article
  16. Article
  17. Advances in Drug Discovery Targeting Lysosomal Membrane Proteins.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  18. NAADP-Mediated CaHandbook of experimental pharmacology · 2023
    Article
  19. T cell CaFrontiers in immunology · 2023
    Review
  20. Two-pore channels: going with the flows.Biochemical Society transactions · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Jonathan S MarchantDepartment of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA. Electronic address: JMarchant@mcw.edu.
Gihan S GunaratneDepartment of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.
Xinjiang CaiDivision of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
James T SlamaDepartment of Medicinal and Biological Chemistry, University of Toledo College of Pharmacy and Pharmaceutical Sciences, 3000 Arlington Avenue, Toledo, OH 43614, USA.
Sandip PatelDepartment of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK. Electronic address: patel.s@ucl.ac.uk.
Medical College of Wisconsin · USMRC Laboratory for Molecular Cell Biology · GBUniversity of California, Los Angeles · USUniversity of Toledo · US

Funding

CARDIOVASCULAR SCIENTIST TRAINING PROGRAMT32HL007895 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SHIVKUMAR, KALYANAM, WATSON, KAROL E · 1998 to 2023
$9.2M
Functional architecture of IP3-evoked local Ca2+ signalsR01GM088790 · NIGMS · UNIVERSITY OF MINNESOTA · PI MARCHANT, JONATHAN S, SLAMA, JAMES T · 2009 to 2025
$4.7M
Identification of the Elusive NAADP ReceptorR15GM131329 · NIGMS · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI SLAMA, JAMES T · 2018 to 2018
$462k
Biotechnology and Biological Sciences Research Council BB/N01524X/1Biotechnology and Biological Sciences Research Council BB/T015853/1NHLBI NIH HHS T32 HL007895NIGMS NIH HHS R01 GM088790NIGMS NIH HHS R15 GM131329
6 · The paper itself

Abstract

Nicotinic acid adenine dinucleotide phosphate (NAADP) is a second messenger that releases Ca

Indexed as

Calcium ChannelsCarrier ProteinsCalciumCalcium SignalingLysosomesNADPCalciumCalcium ChannelsCarrier ProteinsNAADPNADPcalcium signalingcancerendosomeslysosomesphotoaffinity probes

Identifiers

PMID34810081
PMCPMC8840967
OpenAlexW3215961378

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.