Evidence map›Paper›PMID 34809994›Full record

ReviewJournal of psychiatric research2022

Modulating neuroinflammation in COVID-19 patients with obsessive-compulsive disorder.

Vera Nezgovorova, Casara Jean Ferretti, Stefano Pallanti, Eric Hollander

Open access · greenAbstract readReview
In one paragraph

Review in Journal of psychiatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
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  5. Article
  6. Review
  7. Efficacy of a vegetal mixture composed ofFrontiers in nutrition · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Vera NezgovorovaAutism and Obsessive-Compulsive Spectrum Program, Psychiatry Research Institute of Montefiore-Einstein, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
Casara Jean FerrettiAutism and Obsessive-Compulsive Spectrum Program, Psychiatry Research Institute of Montefiore-Einstein, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
Stefano PallantiAutism and Obsessive-Compulsive Spectrum Program, Psychiatry Research Institute of Montefiore-Einstein, Albert Einstein College of Medicine, Bronx, NY, 10461, USA; Istituto di Neuroscienze, Florence, Italy.
Eric HollanderAutism and Obsessive-Compulsive Spectrum Program, Psychiatry Research Institute of Montefiore-Einstein, Albert Einstein College of Medicine, Bronx, NY, 10461, USA. Electronic address: eholland@montefiore.org.
Albert Einstein College of Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exacerbation of symptoms of obsessive-compulsive disorder (OCD) during COVID-19 or new onset of the OCD symptoms resulting from COVID-19 infection is an understudied area of research. It is possible that increased proinflammatory immune status is associated with the onset of obsessive-compulsive symptoms in patients with COVID-19 and that targeted anti-inflammatory treatments for COVID-19 infection can mitigate the new onset of Obsessive-Compulsive (OC) spectrum symptoms. In this review, we cover OCD pathogenesis as related to COVID-19, summarize the impact of cytokines on behavior, and suggest that anti-cytokine treatments can help mitigate post-COVID-19 and new onset of the OC symptoms.

Indexed as

COVID-19Obsessive-Compulsive DisorderHumansNeuroinflammatory DiseasesCOVID-19NeuroinflammationObsessive-compulsive disorderOCD

Identifiers

PMID34809994
PMCPMC8594960
OpenAlexW3213587136

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.