Evidence map›Paper›PMID 34809670›Full record

ArticleBMC sports science, medicine & rehabilitation2021

Impacts of different intensities of exercise on inflammation and hypoxia markers in low altitude.

Fatih Baygutalp, Yusuf Buzdağlı, Murat Ozan, Mitat Koz, Nurcan Kılıç Baygutalp, Gökhan Atasever

Registry-linked trialAbstract read
In one paragraph

Article in BMC sports science, medicine & rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06969898 (Penyagolosa Trail Saludable 2025), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06969898 completednot on this mapstarted 2025, after this paper: background citation

Penyagolosa Trail Saludable 2025

Typeobservational_patient_registrySponsorUniversitat Jaume IRan2025 to 2025Enrolled37ConditionsPhysical ExerciseArmsSingle Ultramarathon runners
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fatih BaygutalpDepartment of Physical Medicine and Rehabilitation, Ataturk University Faculty of Medicine, Erzurum, Turkey. drbaygutalp@gmail.com.
Yusuf BuzdağlıDepartment of Physical Education and Sports, Erzurum Technical University Faculty of Sport Sciences, Erzurum, Turkey.
Murat OzanDepartment of Physical Education and Sports, Ataturk University Kazım Karabekir Education Faculty, Erzurum, Turkey.
Mitat KozDepartment of Sports Health Sciences, Ankara University Faculty of Sport Sciences, Ankara, Turkey.
Nurcan Kılıç BaygutalpDepartment of Biochemistry, Ataturk University Faculty of Pharmacy, Erzurum, Turkey.
Gökhan AtaseverDepartment of Recreation, Ataturk University Faculty of Sport Sciences, Erzurum, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aims to determine and compare the effects of exercise modalities with different intensities on the secretion of key inflammation and hypoxia markers in amateur athletes.

methodsTwenty-three athletes with a mean age of 20.1 years, living at low altitude (1850 m) participated in this study. The participants' maximal oxygen consumption values (VO

resultsThere were significant differences in serum TNF-α levels in 75% VO

conclusionsBoth inflammatory and anti-inflammatory pathway is induced on different exercise intensities. Exercise protocols performed until exhaustion may lead to activation of inflammatory pathways and hypoxia-induced damage.

Indexed as

Anti-inflammatory cytokineExerciseHealthHypoxiaPro-inflammatory cytokine

Identifiers

PMID34809670
PMCPMC8609846

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.