ArticleParticle and fibre toxicology2021
Compositional and structural analysis of engineered stones and inorganic particles in silicotic nodules of exposed workers.
Article in Particle and fibre toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Data-driven optimisation of sustainable high-performance concrete incorporating SCMs, biomass ash, and graphene nanoplatelets.Scientific reports · 2026Article
- The Combined Role of Silanols and Oxidative Stress in Determining Engineered Stone Dust Toxicity.ACS organic & inorganic Au · 2026Article
- Silicosis history: from antiquity to the anthropocene.Frontiers in public health · 2026Article
- Multimodal Fusion of Chest X-Rays and Blood Biomarkers for Automated Silicosis Staging.Journal of clinical medicine · 2025Article
- High metabolic activity in positron emission tomography and systemic inflammation occurring years after exposure cessation in engineered stone silicosis.Scientific reports · 2025Article
- NLRP3 deficiency abrogates silica-induced neutrophil infiltration, pulmonary damage and fibrosis.Respiratory research · 2025Article
- Occupational dust and chemical exposures and the development of autoimmune rheumatic diseases.Nature reviews. Rheumatology · 2025Review
- Burden of silicosis based on the Global Burden of Disease Study 2021: trend analysis of incidence, mortality, and disability-adjusted life years, and projections for the next 30 years.Journal of thoracic disease · 2025Article
- Measuring improvements in occupational health and safety in the artificial stone benchtop industry.Annals of work exposures and health · 2025Article
- Early diagnosis and survival outcomes in silicosis: a retrospective cohort study of 11,809 patients in Guangdong Province, China (1956-2020).Frontiers in public health · 2025Article
- The role of pathologists in the diagnosis of occupational lung diseases: an expert opinion of the European Society of Pathology Pulmonary Pathology Working Group.Virchows Archiv : an international journal of pathology · 2024Review
- From Engineered Stone Slab to Silicosis: A Synthesis of Exposure Science and Medical Evidence.International journal of environmental research and public health · 2024Review
- From Basic Research to Clinical Practice: Considerations for Treatment Drugs for Silicosis.International journal of molecular sciences · 2023Review
- Engineered Stone Fabrication Work Releases Volatile Organic Compounds Classified as Lung Irritants.Annals of work exposures and health · 2023Article
- Progressive massive fibrosis: An overview of the recent literature.Pharmacology & therapeutics · 2022Review
- Inflammatory indices obtained from routine blood tests show an inflammatory state associated with disease progression in engineered stone silicosis patients.Scientific reports · 2022Article
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEngineered stone silicosis is an emerging disease in many countries worldwide produced by the inhalation of respirable dust of engineered stone. This silicosis has a high incidence among young workers, with a short latency period and greater aggressiveness than silicosis caused by natural materials. Although the silica content is very high and this is the key factor, it has been postulated that other constituents in engineered stones can influence the aggressiveness of the disease. Different samples of engineered stone countertops (fabricated by workers during the years prior to their diagnoses), as well as seven lung samples from exposed patients, were analyzed by multiple techniques.
resultsThe different countertops were composed of SiO
conclusionSome of the volatile organic compounds, polycyclic aromatic hydrocarbons and metals detected in the studied countertop samples have been described as causative of lung inflammation and respiratory disease. Among inorganic constituents, aluminum has been a relevant component within the silicotic nodule, reaching atomic concentrations even higher than silicon in some cases. Such concentrations, both for silicon and aluminum showed a decreasing tendency from the center of the nodule towards its frontier.
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