Evidence map›Paper›PMID 34809654›Full record

Observational studyJournal of translational medicine2021

The health risks of dysphagia for patients with head and neck cancer: a multicentre prospective observational study.

Maria Giulia Cristofaro, Ida Barca, Francesco Ferragina, Daniela Novembre, Yvelise Ferro, Roberta Pujia, Tiziana Montalcini

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  20. Evaluating Effective Feeding Methods for Nutritional Management in Head and Neck Cancer Patients Post-Surgery: A Systematic Review.ORL-head and neck nursing : official journal of the Society of Otorhinolaryngology and Head-Neck Nurses · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria Giulia CristofaroDepartment of Experimental and Clinical Medicine, Maxillofacial Surgery Unit, "Magna Graecia" University, Viale Europa, 88100, Catanzaro, Italy. cristofaro@unicz.it.
Ida BarcaDepartment of Experimental and Clinical Medicine, Maxillofacial Surgery Unit, "Magna Graecia" University, Viale Europa, 88100, Catanzaro, Italy.
Francesco FerraginaDepartment of Experimental and Clinical Medicine, Maxillofacial Surgery Unit, "Magna Graecia" University, Viale Europa, 88100, Catanzaro, Italy.
Daniela NovembreDepartment of Experimental and Clinical Medicine, Maxillofacial Surgery Unit, "Magna Graecia" University, Viale Europa, 88100, Catanzaro, Italy.
Yvelise FerroDepartment of Health Science, Nutrition Unit, "Magna Graecia" University, Viale Europa, 88100, Catanzaro, Italy.
Roberta PujiaDepartment of Health Science, Nutrition Unit, "Magna Graecia" University, Viale Europa, 88100, Catanzaro, Italy.
Tiziana MontalciniDepartment of Experimental and Clinical Medicine, Maxillofacial Surgery Unit, "Magna Graecia" University, Viale Europa, 88100, Catanzaro, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is well known that malnutrition is a frequent co-morbidity in cancer patients, especially in those with head and neck neoplasms. This may be due both to the presence of dysphagia symptoms and to the appearance of adverse effects on chemotherapy and / or radiotherapy. The aim of this retrospective observational multicentric study is to evaluate the nutritional status between dysphagia cancer patients and non-dysphagia cancer patients. Data from 60 patients were analysed, 31 of which without dysphagia and 29 with dysphagia. Results highlight that patients with dysphagia had higher involuntary body weight loss than non-dysphagia ones (p < 0.001). By analysing the entire population, it stands out a weight loss rate of 12 ± 9% compared to the usual weight was observed and a prevalence of moderate / severe malnutrition diagnosis of 53%. Furthermore, 76% of the population who manifested the symptom of dysphagia presented severe malnutrition already at the first visit, compared to 32% of non-dysphagia subjects.

Indexed as

Deglutition DisordersHead and Neck NeoplasmsMalnutritionHumansNutritional StatusRetrospective StudiesDysphagiaEnteral nutritionHead and neck cancerMalnutritionMaxillofacial surgery

Identifiers

PMID34809654
PMCPMC8607588

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.