Evidence map›Paper›PMID 34809609›Full record

ArticleBMC infectious diseases2021

Exploring relationships between drought and epidemic cholera in Africa using generalised linear models.

Gina E C Charnley, Ilan Kelman, Nathan Green, Wes Hinsley, Katy A M Gaythorpe, Kris A Murray

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  3. Identification of priority areas for cholera control, Cameroon.Bulletin of the World Health Organization · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Gina E C CharnleySchool of Public Health, Imperial College London, Norfolk Place, London, W2 1PG, UK. g.charnley19@imperial.ac.uk.
Ilan KelmanInstitute for Risk and Disaster Reduction, University College London, London, WC1E 6BT, UK.
Nathan GreenDepartment of Statistical Science, University College London, London, WC1E 6BT, UK.
Wes HinsleySchool of Public Health, Imperial College London, Norfolk Place, London, W2 1PG, UK.
Katy A M GaythorpeSchool of Public Health, Imperial College London, Norfolk Place, London, W2 1PG, UK.
Kris A MurraySchool of Public Health, Imperial College London, Norfolk Place, London, W2 1PG, UK.
Imperial College London · GBMRC Unit the Gambia · GMUniversity College London · GBUniversity of Agder · NO

Funding

Medical Research Council MR/R015600/1Natural Environmental Research Council NE/S007415/1
6 · The paper itself

Abstract

backgroundTemperature and precipitation are known to affect Vibrio cholerae outbreaks. Despite this, the impact of drought on outbreaks has been largely understudied. Africa is both drought and cholera prone and more research is needed in Africa to understand cholera dynamics in relation to drought.

methodsHere, we analyse a range of environmental and socioeconomic covariates and fit generalised linear models to publicly available national data, to test for associations with several indices of drought and make cholera outbreak projections to 2070 under three scenarios of global change, reflecting varying trajectories of CO

resultsThe best-fit model implies that drought is a significant risk factor for African cholera outbreaks, alongside positive effects of population, temperature and poverty and a negative effect of freshwater withdrawal. The projections show that following stringent emissions pathways and expanding sustainable development may reduce cholera outbreak occurrence in Africa, although these changes were spatially heterogeneous.

conclusionsDespite an effect of drought in explaining recent cholera outbreaks, future projections highlighted the potential for sustainable development gains to offset drought-related impacts on cholera risk. Future work should build on this research investigating the impacts of drought on cholera on a finer spatial scale and potential non-linear relationships, especially in high-burden countries which saw little cholera change in the scenario analysis.

Indexed as

CholeraEpidemicsAfricaDisease OutbreaksDroughtsHumansLinear ModelsAfricaCholeraClimate changeDisease outbreaksDroughtsEpidemiologyPublic healthVibrio cholerae

Identifiers

PMID34809609
PMCPMC8609751
OpenAlexW3215426052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.