Evidence map›Paper›PMID 34809459›Full record

ArticlemBio2021

ElyC and Cyclic Enterobacterial Common Antigen Regulate Synthesis of Phosphoglyceride-Linked Enterobacterial Common Antigen.

Ashutosh K Rai, Joseph F Carr, David E Bautista, Wei Wang, Angela M Mitchell

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

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  15. Frontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ashutosh K RaiDepartment of Biology, Texas A&M University, College Station, Texas, USA.
Joseph F Carr *Department of Biology, Texas A&M University, College Station, Texas, USA.
David E Bautista *Department of Biology, Texas A&M University, College Station, Texas, USA.
Wei WangInstitute for Integrative Genomics, Princeton Universitygrid.16750.35, Princeton, New Jersey, USA.
Angela M MitchellDepartment of Biology, Texas A&M University, College Station, Texas, USA.ORCID 0000-0003-1062-0716
Texas A&M University · USPrinceton University · US

Funding

Biogenesis and maintenance of the outer membrane of Gram-negative bacteriaR35GM118024 · NIGMS · PRINCETON UNIVERSITY · PI SILHAVY, THOMAS J. · 2016 to 2025
$8.1M
Biogenesis of cyclic and phospholipid-linked enterobacterial common antigenR01AI155915 · NIAID · TEXAS A&M UNIVERSITY · PI MITCHELL, ANGELA MARIE · 2021 to 2025
$2.0M
NIAID NIH HHS R01 AI155915NIGMS NIH HHS R35 GM118024
6 · The paper itself

Abstract

The Gram-negative cell envelope is a complex structure delineating the cell from its environment. Recently, we found that enterobacterial common antigen (ECA) plays a role maintaining the outer membrane (OM) permeability barrier, which excludes toxic molecules including many antibiotics. ECA is a conserved carbohydrate found throughout

Indexed as

Antigens, BacterialBacterial Outer MembraneBiosynthetic PathwaysEscherichia coliGlycerophospholipidsAntigens, Bacterialenterobacterial common antigenGlycerophospholipidsbiosynthesisenterobacterial common antigenisoprenoidsmetabolic regulationouter membrane

Identifiers

PMID34809459
PMCPMC8609368
OpenAlexW3214847601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.