Evidence map›Paper›PMID 34808616›Full record

ArticleObesity facts2022

Fetal Growth and Adipose Fat Tissue Trajectories in Twin Pregnancies after Gastric Bypass Surgery.

Gülen Yerlikaya-Schatten, Theresa Schönleitner, Michael Feichtinger, Grammata Kotzaeridi, Daniel Eppel, Karen Weißhaupt, Wolfgang Henrich, Christian S Göbl

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Obesity facts, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Gülen Yerlikaya-SchattenDepartment of Obstetrics and Gynecology, Medical University of Vienna, Vienna, Austria, guelen.yerlikaya-schatten@meduniwien.ac.at.
Theresa SchönleitnerDepartment of Obstetrics and Gynecology, Medical University of Vienna, Vienna, Austria.
Michael FeichtingerWunschbaby Institut Feichtinger, Vienna, Austria.
Grammata KotzaeridiDepartment of Obstetrics and Gynecology, Medical University of Vienna, Vienna, Austria.
Daniel EppelDepartment of Obstetrics and Gynecology, Medical University of Vienna, Vienna, Austria.
Karen WeißhauptBerlin Institute of Health, Clinic of Obstetrics, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Wolfgang HenrichBerlin Institute of Health, Clinic of Obstetrics, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Christian S GöblDepartment of Obstetrics and Gynecology, Medical University of Vienna, Vienna, Austria.
Medical University of Vienna · ATHumboldt-Universität zu Berlin · DEWunschbaby Institut für Kinderwunsch · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPrevious studies demonstrated a continuous decline in fetal growth throughout singleton pregnancy after bariatric surgery. However, intrauterine growth in twin pregnancy is subjected to further underlying processes. This study was to investigate the longitudinal assessment of fetal biometry and abdominal fat thickness of twin pregnancies conceived after gastric bypass (GB) surgery and compare them to body mass index-matched (BMIM) and obese (OB) controls. MATERIALS AND

methodsWe retrospectively assessed ultrasound data of 30 women with dichorionic-diamniotic twin pregnancy (11 women after GB surgery, 9 OB mothers with pregestational BMI ≥30 kg/m2, and 10 BMIM and age-matched controls). We assessed fetal growth parameters including fetal subcutaneous adipose tissue thickness (FSCTT) as well as newborn biometry after delivery. Patient characteristics were obtained from the medical records.

resultsThe rise in FSCTT curves was markedly slower in the twin offspring of women with history of GB as compared to the offspring of OB mothers and offspring of BMIM controls. Hence, FSCTT was significantly decreased in the GB offspring as compared to both control groups at 34 weeks of gestation. Also, growth curves of abdominal circumference were decreased in the offspring of GB patients as compared to OB mothers. Infants of mothers with history of GB showed significantly lower birth weight percentiles compared to newborns of OB mothers (27.2 vs. 48.8 pct, p = 0.025). There was no significant difference in inter-twin birth weight difference between the offspring of GB (median: 9.9%, interquartile ranges [IQR]: 6.5-20.0) versus OB (median: 14.6%, IQR: 8.2-21.6) and BMIM controls (median: 9.0%, IQR: 6.3-12.6, p = 0.714).

conclusionsIn summary, intrauterine growth delay in twin pregnancies after GB is assumed to be a multifactorial event with altered metabolism as the most important factor. However, special attention must be paid to the particularity of twin pregnancies as they seem to be subject to other additional mechanism.

Indexed as

Gastric BypassPregnancy, TwinBirth WeightFemaleFetal DevelopmentHumansInfantInfant, NewbornMalePregnancyRetrospective StudiesUltrasonography, PrenatalBariatric surgeryFat tissueFetal growth restrictionGestational diabetesTwin pregnancy

Identifiers

PMID34808616
PMCPMC9021655
OpenAlexW3217782545

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.