Evidence map›Paper›PMID 34808233›Full record

Trial reportThe Journal of investigative dermatology2022

A Randomized Open-Label Clinical Trial of Lipid-Lowering Therapy in Psoriasis to Reduce Vascular Endothelial Inflammation.

Michael S Garshick, Kamelia Drenkova, Tessa J Barrett, Florencia Schlamp, Edward A Fisher, Stuart Katz, Sanja Jelic, Andrea L Neimann, Jose U Scher, James Krueger and 1 more

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of investigative dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Review
  6. Update on Obesity in Psoriasis Patients.Life (Basel, Switzerland) · 2023
    Review
  7. Review
  8. An inflammatory transcriptomic signature in psoriasis associates with future cardiovascular events.Journal of the European Academy of Dermatology and Venereology : JEADV · 2023
    Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Michael S GarshickCenter for the Prevention of Cardiovascular Disease, Department of Medicine, NYU Langone Health, New York, New York, USA; Leon H. Charney Division of Cardiology, Department of Medicine, NYU Langone Health, New York, New York, USA; Cardiovascular Research Center, NYU Langone Health, New York, New York, USA. Electronic address: Michael.Garshick@nyulangone.org.
Kamelia DrenkovaLeon H. Charney Division of Cardiology, Department of Medicine, NYU Langone Health, New York, New York, USA; Cardiovascular Research Center, NYU Langone Health, New York, New York, USA.
Tessa J BarrettLeon H. Charney Division of Cardiology, Department of Medicine, NYU Langone Health, New York, New York, USA; Cardiovascular Research Center, NYU Langone Health, New York, New York, USA.
Florencia SchlampLeon H. Charney Division of Cardiology, Department of Medicine, NYU Langone Health, New York, New York, USA; Cardiovascular Research Center, NYU Langone Health, New York, New York, USA.
Edward A FisherCenter for the Prevention of Cardiovascular Disease, Department of Medicine, NYU Langone Health, New York, New York, USA; Leon H. Charney Division of Cardiology, Department of Medicine, NYU Langone Health, New York, New York, USA; Cardiovascular Research Center, NYU Langone Health, New York, New York, USA.
Stuart KatzLeon H. Charney Division of Cardiology, Department of Medicine, NYU Langone Health, New York, New York, USA.
Sanja JelicDivision of Pulmonary, Allergy & Critical Care Medicine, Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Andrea L NeimannRonald O. Perelman Department of Dermatology, NYU Langone Health, New York, New York, USA.
Jose U ScherPsoriatic Arthritis Center, Division of Rheumatology, Department of Medicine, NYU Langone Health, New York, New York, USA.
James KruegerLaboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA.
Jeffrey S BergerCenter for the Prevention of Cardiovascular Disease, Department of Medicine, NYU Langone Health, New York, New York, USA; Leon H. Charney Division of Cardiology, Department of Medicine, NYU Langone Health, New York, New York, USA; Cardiovascular Research Center, NYU Langone Health, New York, New York, USA; Division of Hematology & Medical Oncology, Department of Medicine, NYU Langone Health, New York, New York, USA; Division of Vascular & Endovascular Surgery, Department of Surgery, NYU Langone Health, New York, New York, USA.
NYU Langone Health · USColumbia University Irving Medical Center · USRockefeller University · US

Funding

Project-005UL1TR001445 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BREDELLA, MIRIAM ANTOINETTE, HOCHMAN, JUDITH S · 2015 to 2025
$103.5M
Institutional Career DevelopmentKL2TR001446 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI PILLINGER, MICHAEL · 2015 to 2025
$6.7M
Vascular endothelial dysfunction in sleep apneaR01HL106041 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI JELIC, SANJA · 2011 to 2025
$6.6M
NRSA Training CoreTL1TR001447 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MICOLI, KEITH J. · 2015 to 2025
$5.9M
Training Program in Cardiovascular SciencesT32HL098129 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Glenn I Fishman, Ira J Goldberg · 2009 to 2026
$5.9M
Mechanisms of Platelet Activity in Vascular DiseaseR35HL144993 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BERGER, JEFFREY S · 2019 to 2025
$5.5M
Platelet Activity and Vascular Health in Systemic Lupus ErythematosusR01HL139909 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BERGER, JEFFREY S, BUYON, JILL P · 2018 to 2022
$4.3M
Employing the gut microbiome to accelerate effective initiation of rheumatoid arthritis therapyR01AR074500 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Renuka Rajendra Nayak, Jose U. Scher · 2019 to 2026
$4.1M
Obstructive Sleep Apnea and Subclinical Lung Injury in Health and DiseaseR01HL137234 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GOTTLIEB, DANIEL J, JELIC, SANJA · 2018 to 2021
$3.2M
Endovascular Health and Platelet Activity in PsoriasisK23HL152013 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GARSHICK, MICHAEL SETH · 2021 to 2025
$865k
Vascular Endothelial Activation in Sleep ApneaR56HL106041 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI JELIC, SANJA · 2016 to 2016
$530k
NCATS NIH HHS KL2 TR001446NCATS NIH HHS TL1 TR001447NCATS NIH HHS UL1 TR001445NHLBI NIH HHS K23 HL152013NHLBI NIH HHS L30 HL143703NHLBI NIH HHS R01 HL106041NHLBI NIH HHS R01 HL137234NHLBI NIH HHS R01 HL139909NHLBI NIH HHS R35 HL144993NHLBI NIH HHS R56 HL106041NHLBI NIH HHS T32 HL098129NIAMS NIH HHS R01 AR074500
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hydroxymethylglutaryl-CoA Reductase InhibitorsPsoriasisHumansInflammationLipidsTreatment OutcomeHydroxymethylglutaryl-CoA Reductase InhibitorsLipids

Identifiers

PMID34808233
PMCPMC9893130
OpenAlexW3216761040

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.