ArticleThe British journal of radiology2022
Diagnostic yield of CT-guided lung biopsies: how can we limit negative sampling?
Article in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 21 citations in OpenAlex.
- Cutting doses, keeping diagnoses: outcomes of protocol optimization for CT-guided lung biopsies.La Radiologia medica · 2026Article
- Article
- [Expert Consensus on Shared Decision-making in the Diagnosis and Treatment of Ground-glass Opacity-featured Lung Adenocarcinoma].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2026Article
- Diagnostic Performance and Radio-Pathologic Correlation of Image-Guided Biopsy in Head and Neck Lesions: A Systematic Review : Short title: Diagnostic Performance and Radio-Pathologic Correlation of Image-Guided Biopsy in Head and Neck Lesions.Galen medical journal · 2026Review
- Computed Tomography-Guided Percutaneous Core Needle Biopsy of Lung Lesions:Sultan Qaboos University medical journal · 2026Article
- Reevaluating Routine Post-Biopsy Chest X-Rays After CT-Guided Lung Biopsy: Incidence of Pneumothorax and Value of Symptom-Based Monitoring.Journal of clinical medicine · 2025Article
- The role of gravitational effects and pre-puncture techniques in reducing pneumothorax during CT-guided lung biopsies.La Radiologia medica · 2025Article
- Deep-learning based electromagnetic navigation system for transthoracic percutaneous puncture of small pulmonary nodules.Scientific reports · 2025Article
- Radiomics-based optimization of target selection in CT-guided percutaneous lung cancer biopsy: a retrospective study.Frontiers in oncology · 2025Article
- The diagnostic value of CT-guided percutaneous lung biopsy in atypical pulmonary hamartoma and pulmonary sclerosing pneumocytoma.Frontiers in oncology · 2025Article
- Histology profiling of lung tumors: tru-cut versus full-core system for CT-guided biopsies.La Radiologia medica · 2024Article
- Establishing clinically meaningful ranges of metal hypersensitivity in orthopaedic patients using COVID-19 vaccine-induced adaptive immune responses from fully vaccinated adults.Journal of orthopaedics · 2024Article
- PET/CT-aided biopsy of lung lesions enhances diagnostic efficacy, especially for lesions >3cm.Frontiers in oncology · 2024Article
- Ability of single anesthesia for combined robotic-assisted bronchoscopy and surgical lobectomy to reduce time between detection and treatment in stage I non-small cell lung cancer.Proceedings (Baylor University. Medical Center) · 2023Article
- CT-Guided Transthoracic Biopsy of Pulmonary Lesions: Diagnostic versus Nondiagnostic Results.Diagnostics (Basel, Switzerland) · 2022Article
- Diagnostic utility and limitations of CT-guided transthoracic fine-needle aspiration biopsy in Lung-RADS 4 pulmonary nodules ≤2 cm.Annals of Saudi medicineArticle
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate whether lesion imaging features may condition the outcome of CT-guided lung biopsy (CTLB) and to develop a scoring system of biopsy outcome prediction.
methodsThis is a single center retrospective study on 319 CTLBs that were performed in 319 patients (167 males/152 females, mean age 68 ± 12.2). Uni- and multivariate analysis were performed aiming to assess the imaging features that are likely to be correlated to a negative biopsy outcome and patients were stratified in groups accordingly.
resultsTechnical success was 100%. 78% of the biopsies (250/319) led to a concrete histology report (218 malignant/32 benign). The remaining lesions led to concrete histology at a second attempt that occurred on a later time. Multivariate analysis revealed increased risk of inconclusive result for nodules with low fludeoxyglucose uptake [odds ration (OR) = 2.64, 95% confidence interval (CI) 1.4-4.97;
conclusionThis study confirms that percutaneous CT-guided biopsy in nodules that are either small in diameter or present low positron emission tomography-fludeoxyglucose uptake or are in one of the lung bases may lead to inconclusive histology. This information should be factored when planning percutaneous biopsies of such nodules in terms of patient informed consent and biopsy strategy. ADVANCES IN KNOWLEDGE: Inconclusive histology after lung biopsy may be subject to factors irrelevant to technical success. Lung biopsy histology outcomes may be predicted and avoided after adequate planning.
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