Evidence map›Paper›PMID 34808042›Full record

ArticleACS biomaterials science & engineering2021

Prefabricated 3D-Printed Tissue-Engineered Bone for Mandibular Reconstruction: A Preclinical Translational Study in Primate.

Shuai-Shuai Cao, Shu-Yi Li, Yuan-Ming Geng, Kausik Kapat, Shang-Bin Liu, Fidel Hugo Perera, Qian Li, Hendrik Terheyden, Gang Wu, Yue-Juan Che and 2 more

Open access · hybridAbstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. TranslatingFrontiers in bioengineering and biotechnology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

Shuai-Shuai CaoDepartment of Oral and Maxillofacial Surgery, Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou 510182, China.
Shu-Yi LiDepartment of Oral and Maxillofacial Surgery, Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou 510182, China.
Yuan-Ming GengDepartment of Stomatology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
Kausik KapatDepartment of Oral and Maxillofacial Surgery, Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou 510182, China.
Shang-Bin LiuDepartment of Oral and Maxillofacial Surgery, Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou 510182, China.
Fidel Hugo PereraDepartment of Mechanical, Energy and Materials Engineering, University of Extremadura, Industrial Engineering School, Avda. de Elvas s/n, 06006 Badajoz, Spain.
Qian LiHangzhou Jiuyuan Gene Engineering Co., Ltd., Hangzhou 3100018, China.
Hendrik TerheydenDepartment of Oral and Maxillofacial Surgery, Red Cross Hospital, Kassel 34117, Germany.
Gang WuDepartment of Oral Implantology and Prosthetic Dentistry, Academic Center for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam 1117, The Netherlands.ORCID 0000-0001-8941-2500
Yue-Juan CheDepartment of Anesthesia, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China.
Pedro MirandaDepartment of Mechanical, Energy and Materials Engineering, University of Extremadura, Industrial Engineering School, Avda. de Elvas s/n, 06006 Badajoz, Spain.
Miao ZhouDepartment of Oral and Maxillofacial Surgery, Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou 510182, China.ORCID 0000-0003-0788-1923
Stomatology Hospital · CNAcademic Center for Dentistry Amsterdam · NLUniversidad de Extremadura · ESGerman Red Cross · DESun Yat-sen University · CNZhujiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The advent of three dimensionally (3D) printed customized bone grafts using different biomaterials has enabled repairs of complex bone defects in various in vivo models. However, studies related to their clinical translations are truly limited. Herein, 3D printed poly(lactic-

Indexed as

Mandibular ReconstructionAnimalsMandiblePositron Emission Tomography Computed TomographyPrimatesPrinting, Three-DimensionalTissue Scaffolds3D printingbone graftmandibular reconstructionPLGA/TCPprefabricationTCP

Identifiers

PMID34808042
PMCPMC8672350
OpenAlexW3214789678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.