Evidence map›Paper›PMID 34807761›Full record

ArticleAntimicrobial agents and chemotherapy2022

Activity of Oritavancin against Gram-Positive Pathogens Causing Bloodstream Infections in the United States over 10 Years: Focus on Drug-Resistant Enterococcal Subsets (2010-2019).

Cecilia G Carvalhaes, Helio S Sader, Jennifer M Streit, Mariana Castanheira, Rodrigo E Mendes

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07013552 (Oritavancin as a Therapeutic Regimen for Cardiac Implantable Electronic Devices Infections With Multidrug-resistant Gram-positive Cocci), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07013552 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Oritavancin as a Therapeutic Regimen for Cardiac Implantable Electronic Devices Infections With Multidrug-resistant Gram-positive Cocci

TypeinterventionalSponsorMedical University of SilesiaRan2025 to 2026Enrolled100ConditionsCardiac Implantable Electronic Device Infections, Infective Endocarditis, Multidrug-resistant Bacteria Screening, Gram Positive Bacterial InfectionArmsAdministration of a single or repeated dose of a long half-life antibiotic - oritavancin, Administration of a repeated dose of a short half-life antibiotic - vancomycin
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. ManagingEClinicalMedicine · 2026
    Article
  5. Article
  6. Article
  7. Oritavancin safety: a real-world pharmacovigilance study of the FAERS database.Frontiers in cellular and infection microbiology · 2026
    Article
  8. Article
  9. Review
  10. Genomic Epidemiology of Vancomycin-ResistantAntibiotics (Basel, Switzerland) · 2025
    Article
  11. Observational
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Cecilia G CarvalhaesJMI Laboratoriesgrid.419652.d, North Liberty, Iowa, USA.ORCID 0000-0002-2734-3754
Helio S SaderJMI Laboratoriesgrid.419652.d, North Liberty, Iowa, USA.ORCID 0000-0001-7022-6644
Jennifer M StreitJMI Laboratoriesgrid.419652.d, North Liberty, Iowa, USA.ORCID 0000-0002-8419-6308
Mariana CastanheiraJMI Laboratoriesgrid.419652.d, North Liberty, Iowa, USA.ORCID 0000-0003-0126-1782
Rodrigo E MendesJMI Laboratoriesgrid.419652.d, North Liberty, Iowa, USA.ORCID 0000-0002-8648-1137
JMI Laboratories · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oritavancin displayed potent and stable activity (MIC

Indexed as

Anti-Bacterial AgentsGram-Positive Bacterial InfectionsLipoglycopeptidesMethicillin-Resistant Staphylococcus aureusSepsisVancomycin-Resistant EnterococciHumansMicrobial Sensitivity TestsUnited StatesVancomycinAnti-Bacterial AgentsLipoglycopeptidesoritavancinVancomycindaptomycin resistanceE. faeciumlipoglycopeptidesVanAVanBvancomycin resistanceVRE

Identifiers

PMID34807761
PMCPMC8846398
OpenAlexW3215409706

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.