Evidence map›Paper›PMID 34807749›Full record

ArticleCell transplantation

Mesenchymal Stem/Stromal Cells Overexpressing CXCR4

Hamid Reza Bidkhori, Ahmad Reza Bahrami, Moein Farshchian, Asieh Heirani-Tabasi, Mahdi Mirahmadi, Halimeh Hasanzadeh, Naghmeh Ahmadiankia, Reza Faridhosseini, Mahtab Dastpak, Arezoo Gowhari Shabgah and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Hamid Reza BidkhoriStem Cells and Regenerative Medicine Research Group, Academic Center for Education, Culture, and Research (ACECR)-Khorasan Razavi, Mashhad, Iran.
Ahmad Reza BahramiDepartment of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.
Moein FarshchianStem Cells and Regenerative Medicine Research Group, Academic Center for Education, Culture, and Research (ACECR)-Khorasan Razavi, Mashhad, Iran.
Asieh Heirani-TabasiStem Cells and Regenerative Medicine Research Group, Academic Center for Education, Culture, and Research (ACECR)-Khorasan Razavi, Mashhad, Iran.
Mahdi MirahmadiStem Cells and Regenerative Medicine Research Group, Academic Center for Education, Culture, and Research (ACECR)-Khorasan Razavi, Mashhad, Iran.
Halimeh HasanzadehStem Cells and Regenerative Medicine Research Group, Academic Center for Education, Culture, and Research (ACECR)-Khorasan Razavi, Mashhad, Iran.
Naghmeh AhmadiankiaShahroud University of Medical Sciences, Shahroud, Iran.
Reza FaridhosseiniDepartment of Immunology, Mashhad Universityof Medical Sciences, Mashhad, Iran.
Mahtab DastpakStem Cells and Regenerative Medicine Research Group, Academic Center for Education, Culture, and Research (ACECR)-Khorasan Razavi, Mashhad, Iran.
Arezoo Gowhari ShabgahSchool of Medicine, Bam University of Medical Sciences, Bam, Iran.
Maryam M MatinStem Cells and Regenerative Medicine Research Group, Academic Center for Education, Culture, and Research (ACECR)-Khorasan Razavi, Mashhad, Iran.ORCID 0000-0002-7949-7712
Academic Center for Education, Culture and Research · IRBam University of Medical Sciences · IRFerdowsi University of Mashhad · IRMashhad University of Medical Sciences · IRShahroud University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

C-X-C chemokine receptor type 4 (CXCR4), initially recognized as a co-receptor for HIV, contributes to several disorders, including the WHIM (Warts, Hypogammaglobulinemia, Infections, and Myelokathexis) syndrome. CXCR4 binds to its ligand SDF-1 to make an axis involved in the homing property of stem cells. This study aimed to employ WHIM syndrome pathogenesis as an inspirational approach to reinforce cell therapies. Wild type and WHIM-type variants of the

Indexed as

Cell MovementHumansMesenchymal Stem CellsPrimary Immunodeficiency DiseasesReceptors, CXCR4WartsCXCR4 protein, humanReceptors, CXCR4CXCR4R334Xhominglentiviral transductionmesenchymal stem cellsWHIM syndrome

Identifiers

PMID34807749
PMCPMC8647223
OpenAlexW3216781293

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.