ArticleInternational urology and nephrology2022
Prevalence, risk factors and clinical characteristics of renal dysfunction in Chinese outpatients with growth simple renal cysts.
Article in International urology and nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 11 citations in OpenAlex.
- The Efficacy and Safety of Dehydrated Alcohol Versus Lauromacrogol for Sclerotherapy of Simple Renal Cysts: A Retrospective Comparison Study.Health science reports · 2026Article
- GGPS1 Promoter Variant (rs3806394) Is Associated With Larger Simple Renal Cysts via Reduced GGPPS Expression.Human mutation · 2026Article
- Association between renal function and simple renal cyst growth: a retrospective study.European journal of medical research · 2025Article
- Review
- Exploring the location patterns and clinical characteristics of isolated simple renal cysts: insights from a multicenter retrospective study.World journal of urology · 2025Article
- Factors Affecting the Presence of Renal Cortical Cysts in Kidney Donors.Urology research & practice · 2025Article
- The prevalence and associated risk factors of detectable renal morphological abnormalities in acromegaly.Pituitary · 2024Article
- Influence of a simple cyst on kidney function.Frontiers in medicine · 2024Article
- Epidemiological Characterisation of Chronic Diseases Among Civil Servants in Hebei Province, China: A Cross-Sectional Real-World Study of Approximately 50,000 Adults.Risk management and healthcare policy · 2024Article
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Authors and funding
5 authors at 2 institutions in 1 country.
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Abstract
backgroundResearchers have proved that simple renal cysts (SRCs) might be correlated with renal dysfunction, but it is still controversial. Thus, we conducted clinical research study with large sample size and long-term follow-up to clarify the relationship between SRCs and renal dysfunction.
methodsA total of 571 SRCs patients in outpatients of nephrology department were included, we investigated the clinical characteristics of growth SRCs compared with non-growth SRCs, evaluated the incidence of renal dysfunction in SRCs and explored the risk factors of renal dysfunction in growth SRCs.
resultsThe mean baseline age was 51.31 ± 14.37 years in the whole cohort, ranging from 19 to 79 years, and 57.6% of them were male. The median follow-up duration was 3 years, ranging from 1 to 10 years. In addition, the final maximum diameter increased 1 mm (2.74%) per year. Patients in growth SRCs group tented to have higher percentage of hypertension, hematuria, large cyst and multiple cysts compared with non-growth SRCs group. The prevalence of renal dysfunction was 15.6% after the follow-up, and the prevalence of renal dysfunction was about 10 times higher in growth SRCs group than non-growth SRCs group (23.3% vs. 2.4%). Renal dysfunction was significantly associated with age, female, total cholesterol, diastolic blood pressure, final maximum diameter and yearly change in maximum diameter in growth SRCs.
conclusionsSRCs were closely related to the decline of renal function, we recommend close follow-up for growth SRCs.
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