Evidence map›Paper›PMID 34807345›Full record

ReviewOdontology2022

The use of hydroxyapatite toothpaste to prevent dental caries.

Kelsey O'Hagan-Wong, Joachim Enax, Frederic Meyer, Bernhard Ganss

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Odontology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed.

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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kelsey O'Hagan-WongFaculty of Dentistry, University of Toronto, 124 Edward St., Toronto, M5G 1G6, Canada.
Joachim EnaxResearch Department, Oral Care Dr. Kurt Wolff GmbH & Co. KG, Johanneswerkstr, 34-36, 33611, Bielefeld, Germany.
Frederic MeyerResearch Department, Oral Care Dr. Kurt Wolff GmbH & Co. KG, Johanneswerkstr, 34-36, 33611, Bielefeld, Germany.
Bernhard GanssFaculty of Dentistry, University of Toronto, 124 Edward St., Toronto, M5G 1G6, Canada. b.ganss@dentistry.utoronto.ca.ORCID http://orcid.org/0000-0002-5280-978X

Funding

National Science and Engineering Research Council (NSERC) of Canada RGPIN-2019-07070
6 · The paper itself

Abstract

Dissolution of hydroxyapatite from the tooth structure at low pH can lead to the irreversible destruction of enamel and dentin, which if left untreated can result in pain and tooth loss. Hydroxyapatite toothpastes contain hydroxyapatite particles in micro- or nanocrystalline form that have been shown to deposit and restore demineralized enamel surfaces. As such, they are currently being explored as a fluoride-free anti-caries agent. This narrative review article aims to summarize the recent findings of the research investigating the remineralization potential of HAP toothpaste in vitro, in situ and in vivo, as well as some other applications in dentistry.

Indexed as

Dental CariesToothpastesCariostatic AgentsDurapatiteFluoridesHumansTooth RemineralizationCariostatic AgentsDurapatiteFluoridesToothpastesEnamelHydroxyapatiteOral careToothpaste

Identifiers

PMID34807345
PMCPMC8930857

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.