Evidence map›Paper›PMID 34807316›Full record

ArticleThe international journal of cardiovascular imaging2022

Reference values for left ventricular dimensions, systolic and diastolic function: a study from the Amazon Basin of Brazil.

Alma Wegener, Molly D Kaagaard, Laura Cordeiro Gomes, Anna Engell Holm, Luan O Matos, Karine O Lima, Isabelle V M Vieira, Rodrigo Medeiros de Souza, Flemming Javier Olsen, Claudio Romero Farias Marinho and 3 more

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in The international journal of cardiovascular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04445103 (The Malaria Heart Disease Study), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04445103 terminatednot on this map

The Malaria Heart Disease Study: A Novel Pathway to Subclinical Heart Disease

TypeobservationalSponsorUniversity Hospital, Gentofte, CopenhagenRan2020 to 2021Enrolled597ConditionsPlasmodium Falciparum, Plasmodium Vivax, Heart Diseases, Cardiovascular DiseasesArmsAssessment of cardiac function
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Alma Wegener *Multidisciplinary Center, Federal University of Acre, Câmpus Floresta, Cruzeiro do Sul, Acre, Brazil.
Molly D Kaagaard *Multidisciplinary Center, Federal University of Acre, Câmpus Floresta, Cruzeiro do Sul, Acre, Brazil.
Laura Cordeiro GomesDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Anna Engell HolmMultidisciplinary Center, Federal University of Acre, Câmpus Floresta, Cruzeiro do Sul, Acre, Brazil.
Luan O MatosMultidisciplinary Center, Federal University of Acre, Câmpus Floresta, Cruzeiro do Sul, Acre, Brazil.
Karine O LimaMultidisciplinary Center, Federal University of Acre, Câmpus Floresta, Cruzeiro do Sul, Acre, Brazil.
Isabelle V M VieiraMultidisciplinary Center, Federal University of Acre, Câmpus Floresta, Cruzeiro do Sul, Acre, Brazil.
Rodrigo Medeiros de SouzaMultidisciplinary Center, Federal University of Acre, Câmpus Floresta, Cruzeiro do Sul, Acre, Brazil.
Flemming Javier OlsenCardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Hellerup, Denmark.
Claudio Romero Farias MarinhoDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Tor Biering-SørensenCardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Hellerup, Denmark.
Odilson M SilvestreHealth and Sport Science Center, Federal University of Acre, Rio Branco, Acre, Brazil.
Philip BraininMultidisciplinary Center, Federal University of Acre, Câmpus Floresta, Cruzeiro do Sul, Acre, Brazil. pjen0286@regionh.dk.ORCID http://orcid.org/0000-0001-6880-0424
Universidade Federal do Acre · BRUniversidade de São Paulo · BRGentofte Hospital · DKUniversity of Copenhagen · DK

Funding

CNPQ 142306/2020-7CNPQ 302917/2019-5dansk medicinsk selskab københavn 120620-kmsEva og Henry Frænkels Mindefond NLA-080919FAPESP 2020/06747-4Fonden til Lægevidenskabens Fremme 18-L-0026Hjerteforeningen 20-R139-A9644-22165Knud Højgaards Fond 18-05-2487Knud Højgaards Fond 20-01-1076Lundbeckfonden R373-2021-1201Novo Nordisk Fonden NNF20OC0062782Reinholdt W. Jorck og Hustrus Fond 18-JU-2487Reinholdt W. Jorck og Hustrus Fond 20-JU-0145Sundhed og Sygdom, Det Frie Forskningsråd 0129-0003bTorben og Alice Frimodts Fond TA250419William Demant 20-1257
6 · The paper itself

Abstract

Country- and ethnicity-specific reference values for echocardiographic parameters are necessary for decision making. No prior studies have examined reference values in adults from the Amazon Basin of Brazil. We performed echocardiographic examinations in 290 healthy adults (mean age 37 ± 14 years, 40% male) from the Brazilian Amazon. Left ventricular (LV) dimensions and volumes were obtained and indexed to body surface area. We also assessed systolic (LV ejection fraction [LVEF] and global longitudinal strain [GLS]) and diastolic function. LV dimensions and volumes were larger in males compared to females, but after indexation only volumes remained larger (P < 0.001 for all). Parameters of systolic function, were significantly greater in females (LVEF 50 to 68%, GLS - 17 to - 24%) than in males (LVEF 50 to 67%, GLS - 15 to - 23%, P < 0.05). Upper limits of normality for cardiac dimensions (indexed and non-indexed) were markedly higher compared to contemporary guidelines (American Society of Echocardiography) and the Brazilian subgroup in the World Alliance Society of Echocardiography (WASE). Lower limit of normality for LVEF (both sex 50%) and upper limit of normality for the left atrial volume index (LAVI) (male: 31 mL/m

Indexed as

BrazilDiastolic functionEchocardiographyLeft ventricular dimensionLeft ventricular volumeNormal valuesSystolic function

Identifiers

PMID34807316
OpenAlexW3215980828

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.