Trial reportUrolithiasis2022
Retrograde intrarenal surgery versus percutaneous nephrolithotomy for treatment of renal pelvic stone more than 2 centimeters: a prospective randomized controlled trial.
Trial report in Urolithiasis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Percutaneous nephrolithotomy versus retrograde intrarenal surgery for treatment of renal stones in adults.The Cochrane database of systematic reviews · 2023Pooled it
- Efficacy and safety of various endosurgical procedures for management of large renal stone: a systemic review and network meta-analysis of randomised control trials.Urolithiasis · 2023Pooled it
- Intelligent pressure-controlled retrograde intrarenal surgery versus microchannel percutaneous nephrolithotomy to treat 2-3 cm renal calculi.Urolithiasis · 2025Trial
- Is flexible navigable suction ureteral access sheath (FANS) safer and more efficient than conventional sheaths? Italian multicentric experience.World journal of urology · 2025Trial
- Clinical evaluation and related factor analysis of intrarenal pressure using a Chinese-made disposable pressure-measuring flexible ureteroscope.The Canadian journal of urology · 2026Article
- Impact of ureteral access sheath size on intrarenal pressure evaluated by LithoVueInternational urology and nephrology · 2025Article
- Feasibility of respiratory synchronization for laser lithotripsy using a robotic retrograde intrarenal surgery system Zamenix™ in an in-vitro model.European journal of medical research · 2025Article
- Comparison of three different scoring systems in predicting success of retrograde intrarenal surgery in kidney stones larger than 20 millimeters.World journal of urology · 2024Article
- Clinical efficacy analysis of tip‑flexible suctioning ureteral access sheath combined with disposable flexible ureteroscope to treat 2-4 cm renal stones.International urology and nephrology · 2024Article
- Article
- Assessment of Factors Responsible for Stone-Free Status After Retrograde Intrarenal Surgery.Cureus · 2024Article
- New infundibulopelvic angle measurement method can predict stone-free rates following retrograde intrarenal surgery.Scientific reports · 2024Article
- Comparison of traditional and novel tip-flexible suctioning ureteral access sheath combined with flexible ureteroscope to treat unilateral renal calculi.World journal of urology · 2023Article
- The Prime Time for Flexible Ureteroscopy for Large Renal Stones Is Coming: Is Percutaneous Nephrolithotomy No Longer Needed?Urology research & practice · 2023Article
- Flexible ureteroscopic lithotripsy with a suctioning ureteral access sheath for removing upper urinary calculi under local anesthesia.Frontiers in surgery · 2023Article
- Validation of the Trifecta Scoring Metric in Vacuum-Assisted Mini-Percutaneous Nephrolithotomy: A Single-Center Experience.Journal of clinical medicine · 2022Article
- Urologists are optimistic surgeons: prevalence and predictors of discordance between intraoperative stone-free rate and cross-sectional imaging evaluation after vacuum-assisted mini-percutaneous nephrolithotomy.World journal of urology · 2022Article
- Comparison of flexible ureteroscopy and mini-percutaneous nephrolithotomy in the treatment for renal calculi larger than 2 cm: a matched-pair analysis.Urolithiasis · 2022Article
- Pelvic stone angle as a novel parameter for predicting stone-free rates after RIRS: A retrospective comparative analysis with established scoring systems-AUSET collaboration.Therapeutic advances in urologyArticle
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed at investigating the efficacy and safety of retrograde intrarenal surgery (RIRS) in treatment of renal pelvic stone larger than 2 cm against the percutaneous nephrolithotomy (PCNL). Between March 2018 and December 2020, 121 patients were randomized to undergo PCNL (60 patients), or RIRS (61 patients). Both groups were compared in terms of operative time, intraoperative complications. Postoperative complications were assessed based on Clavien-Dindo grading system. Stone-free rates were evaluated by CT scan 6 weeks after surgery. No significant difference were observed between both groups in perioperative criteria. The main operative time was slightly longer in PCNL group (105 vs 95 min, p = 0.49). Stone clearance was higher in PCNL, yet the difference was not significant. (53 patients in PCNL group had either complete clearance or residual fragments < 4 mm, compared to 49 in RIRS group (p = 0.22). Blood transfusion rate was 8.3% in PCNL compared to 1.6% in RIRS group, with a trend towards significance (p = 0.08). Post-operative fever was higher in RIRS, yet it fell just short of statistical significance (13.1% vs 5.0%, p = 0.12). Compared to PCNL, RIRS displayed acceptable efficacy with less risk of bleeding requiring transfusion. It can be applied to patients with large renal pelvic stone as an alternative to PCNL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.