Evidence map›Paper›PMID 34806935›Full record

ArticleJournal of medical screening2022

Faecal haemoglobin concentrations in women and men diagnosed with colorectal cancer in a national screening programme.

Gavin Rc Clark, Jayne Digby, Callum G Fraser, Judith A Strachan, Robert Jc Steele

Open access · hybridAbstract read
In one paragraph

Article in Journal of medical screening, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Gender and sex differences in colorectal cancer screening, diagnosis and treatment.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Gavin Rc Clark9571Public Health Scotland, Edinburgh, Scotland, UK.
Jayne DigbyCentre for Research into Cancer Prevention and Screening, 85326University of Dundee, Dundee, Scotland, UK.
Callum G FraserCentre for Research into Cancer Prevention and Screening, 85326University of Dundee, Dundee, Scotland, UK.ORCID 0000-0002-1333-7994
Judith A StrachanBlood Sciences and Scottish Bowel Screening Laboratory, Dundee, Scotland, UK.
Robert Jc SteeleCentre for Research into Cancer Prevention and Screening, 85326University of Dundee, Dundee, Scotland, UK.ORCID 0000-0003-4248-6785
University of Dundee · GBPublic Health Scotland · GBScottish National Blood Transfusion Service · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThere is evidence that colorectal cancer screening using faecal haemoglobin is less effective in women than men. The faecal haemoglobin concentrations were therefore examined in women and men with screen-detected colorectal cancer.

settingScottish Bowel Screening Programme, following the introduction of a faecal immunochemical test from November 2017, to March 2020

methodsData were collated on faecal haemoglobin concentrations, pathological stage and anatomical site of the main lesion in participants who had colorectal cancer detected. The data in women and men were compared.

resultsFor the faecal haemoglobin concentrations studied (

conclusionsTo minimise gender inequalities, faecal immunochemical test-based colorectal cancer screening programmes should evaluate a strategy of using different faecal haemoglobin concentration thresholds in women and men.

Indexed as

Colorectal NeoplasmsEarly Detection of CancerFecesFemaleHemoglobinsHumansMaleMass ScreeningOccult BloodHemoglobinsColorectal cancer screeningcolorectal cancer sitecolorectal cancer stagefaecal haemoglobinfaecal immunochemical testgender differences

Identifiers

PMID34806935
PMCPMC8892068
OpenAlexW3215785400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.