ArticleActa paediatrica (Oslo, Norway : 1992)2022
Population-based study of multisystem inflammatory syndrome associated with COVID-19 found that 36% of children had persistent symptoms.
Article in Acta paediatrica (Oslo, Norway : 1992), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Post-MIS-C cardiovascular outcomes: a systematic review.European journal of pediatrics · 2026Pooled it
- Robustness of reported postacute health outcomes in children with SARS-CoV-2 infection: a systematic review.Archives of disease in childhood · 2023Pooled it
- Pediatrics advances in 2024: choices in allergy, cardiology, critical care, endocrinology, gastroenterology, immunology, infectious diseases, neonatology, nephrology, neurology, nutrition, palliative care respiratory tract illnesses, and social media.Italian journal of pediatrics · 2025Review
- Six-Month Outcomes in the Long-Term Outcomes After the Multisystem Inflammatory Syndrome in Children Study.JAMA pediatrics · 2025Article
- Short-term and medium-term clinical outcomes of multisystem inflammatory syndrome in children: a prospective observational cohort study.Italian journal of pediatrics · 2024Observational
- Short-, mid-, and long-term complications after multisystem inflammatory syndrome in children over a 24-month follow-up period in a hospital in Lima-Peru, 2020-2022.Frontiers in pediatrics · 2023Article
- Short- and mid-term outcomes of multisystem inflammatory syndrome in children: a longitudinal prospective single-center cohort study.Frontiers in pediatrics · 2023Article
- Risk factors for health impairments in children after hospitalization for acute COVID-19 or MIS-C.Frontiers in pediatrics · 2023Article
- Comparison of Long-Term Complications of COVID-19 Illness among a Diverse Sample of Children by MIS-C Status.International journal of environmental research and public health · 2022Article
- Health Impairments in Children and Adolescents After Hospitalization for Acute COVID-19 or MIS-C.Pediatrics · 2022Article
- Risk factors for multisystem inflammatory syndrome in children - A population-based cohort study of over 2 million children.The Lancet regional health. Europe · 2022Article
- The Multifaceted Manifestations of Multisystem Inflammatory Syndrome during the SARS-CoV-2 Pandemic.Pathogens (Basel, Switzerland) · 2022Review
- Convulsions in children with COVID-19 during the Omicron wave.Acta paediatrica (Oslo, Norway : 1992) · 2022Article
- Review
- Population-based study of multisystem inflammatory syndrome associated with COVID-19 found that 36% of children had persistent symptoms.Acta paediatrica (Oslo, Norway : 1992) · 2022Article
Corrections and comments
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Authors and funding
25 authors at 12 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimOur aim was to describe the outcomes of multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19.
methodsThis national, population-based, longitudinal, multicentre study used Swedish data that were prospectively collected between 1 December 2020 and 31 May 2021. All patients met the World Health Organization criteria for MIS-C. The outcomes 2 and 8 weeks after diagnosis are presented, and follow-up protocols are suggested.
resultsWe identified 152 cases, and 133 (87%) participated. When followed up 2 weeks after MIS-C was diagnosed, 43% of the 119 patients had abnormal results, including complete blood cell counts, platelet counts, albumin levels, electrocardiograms and echocardiograms. After 8 weeks, 36% of 89 had an abnormal patient history, but clinical findings were uncommon. Echocardiogram results were abnormal in 5% of 67, and the most common complaint was fatigue. Older children and those who received intensive care were more likely to report symptoms and have abnormal cardiac results.
conclusionMore than a third (36%) of the patients had persistent symptoms 8 weeks after MIS-C, and 5% had abnormal echocardiograms. Older age and higher levels of initial care appeared to be risk factors. Structured follow-up visits are important after MIS-C.
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