Evidence map›Paper›PMID 34806771›Full record

ArticleNeurourology and urodynamics2022

Geometric analysis of the urethral-vaginal interface curvature in women with and without stress urinary incontinence: A pilot magnetic resonance imaging study.

Christopher X Hong, David D Sheyn, Anne G Sammarco, John O DeLancey

Open access · greenAbstract read
In one paragraph

Article in Neurourology and urodynamics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Christopher X HongObstetrics and Gynecology, Pennsylvania Hospital, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-1294-4132
David D SheynPelvic Anatomy Group - Imaging, Society of Gynecologic Surgeons, East Dundee, Illinois, USA.
Anne G SammarcoPelvic Anatomy Group - Imaging, Society of Gynecologic Surgeons, East Dundee, Illinois, USA.ORCID 0000-0003-4926-4560
John O DeLanceyPelvic Anatomy Group - Imaging, Society of Gynecologic Surgeons, East Dundee, Illinois, USA.
University of Michigan · USRush University Medical Center · USSociety of Thoracic Surgeons · US

Funding

Development of 21st Century Concepts and Tools for Quantifying Urethral Failure Mechanisms that Cause Urinary IncontinenceRC2DK122379 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ASHTON-MILLER, JAMES ANTHONY, DELANCEY, JOHN O.L. · 2019 to 2024
$5.7M
NIDDK NIH HHS RC2 DK122379
6 · The paper itself

Abstract

aimsTo evaluate differences in the curvature of the urethral-vaginal interface in women with and without stress urinary incontinence (SUI) using geometric morphometric analysis techniques.

methodsWe conducted a pilot case-control study using magnetic resonance imaging (MRI) scans of 18 women with and without SUI. The urethral-vaginal interface at the level of the mid-urethra was fitted with a second-order polynomial regression. The chord length and chord-to-vertex length of the resulting parabolic curve were used to calculate the arc length and radius of a circular arc fitted to the interface curvature. Demographic characteristics and Pelvic Organ Prolapse Quantification (POP-Q) parameters were collected. Subjects were stratified by those with and without SUI, as well as by those with and without anterior wall prolapse beyond 2 cm proximal to the hymen (Aa > -2 cm).

resultsThe radius of the urethral-vaginal interface curvature was not found to be different between subjects with and without SUI (8.8 vs. 9.2 mm, p = 0.53); however, this value was smaller in subjects with Aa > -2 (8.4 vs. 11.9 mm, p = 0.03). The chord length, chord-to-vertex length, and arc length comprising the urethral-vaginal interface curvature were similar between subjects with and without SUI, and between subjects with and without Aa > -2 cm (p > 0.05 for all).

conclusionsIn this pilot study population, the radius of the urethral-vaginal interface curvature at the mid-urethra was smaller among women with anterior vaginal wall prolapse beyond 2 cm proximal to the hymen. A difference in the urethral-vaginal interface curvature among women with and without SUI was not found.

Indexed as

Pelvic Organ ProlapseUrinary Incontinence, StressCase-Control StudiesFemaleHumansMagnetic Resonance ImagingPilot ProjectsUrethrageometric morphometric analysisMRIpelvic supportstress urinary incontinenceurethral support

Identifiers

PMID34806771
PMCPMC8738156
OpenAlexW3214949810

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.