Evidence map›Paper›PMID 34806659›Full record

SynthesisSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association

Short versus long esophageal myotomy during peroral endoscopic myotomy: A systematic review and meta-analysis of comparative trials.

Zaheer Nabi, Rupjyoti Talukdar, Harshal Mandavdhare, D Nageshwar Reddy

2 registry-linked trialsOpen access · diamondAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06883175 narecruitingnot on this map

Evolution of the Chicago Classification: Bridging Physiology and Mechanics

TypeinterventionalSponsorNorthwestern UniversityRan2024 to 2029Enrolled575ConditionsDysphagia, Achalasia, Esophageal, Ineffective Esophageal MotilityArmsFLIP, HRM, Prucalopride
NCT07325071 nanot yet recruitingnot on this map

A Randomized Controlled Trial Comparing Conventional and Short Submucosal Tunnel Techniques in Type II Achalasia

TypeinterventionalSponsorAsian Institute of Gastroenterology, IndiaRan2025 to 2027Enrolled636ConditionsEsophageal DiseasesArmsArm A - Conventional POEM (Control Arm), Arm B - Standard Tunnel with EGJ complex-only Myotomy, Arm C - Ultra-short Tunnel POEM with EGJ complex -only Myotomy
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Saudi Gastroenterology Association (SGA) clinical care pathway and standards of care for peroral endoscopic myotomy (POEM) in achalasia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Peroral endoscopic myotomy (POEM) for achalasia in the Middle East: The type of myotomy matters.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Zaheer NabiDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India.
Rupjyoti TalukdarDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India.
Harshal MandavdhareDepartment of Gastroenterology, PGIMER, Chandigarh, India.
D Nageshwar ReddyDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India.
Asian Institute of Gastroenterology · INPost Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: : Peroral endoscopic myotomy (POEM) is an established modality of treatment for achalasia cardia. Considerable variations exist in the technique of POEM with respect to the length and orientation of the myotomy. In this systematic review and meta-analysis, we compared the outcomes of short versus long myotomy during POEM. Methods: : We searched multiple databases from January 2010 to March 2021 to identify studies reporting on POEM. We selected studies that reported on comparative outcomes of POEM using short versus long myotomy. We performed a comparative analysis of clinical success, procedural duration, gastroesophageal reflux disease (GERD), and adverse events with short and long myotomy in POEM by meta-analysis. Results: : A total of 521 patients from five studies in which 241 patients were treated with short and 280 patients with long myotomy approaches were analyzed. The pooled rate for clinical success gave an odds ratio (OR) of 1.27 (95% confidence interval [CI] 0.50-3.26; I Conclusion: : Short myotomy and long myotomy in POEM seem comparable with each other in terms of clinical success and adverse events. Short myotomy is associated with significantly shorter procedural duration and possibly reduced esophageal acid exposure compared with long myotomy.

Indexed as

Esophageal AchalasiaGastroesophageal RefluxMyotomyEsophageal Sphincter, LowerHumansTreatment OutcomeAchalasiaendoscopyesophagusmyotomyoutcomes

Identifiers

PMID34806659
PMCPMC9408737
OpenAlexW3212549812

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.